ICD-10 Diagnosis Code E85.0

Non-neuropathic heredofamilial amyloidosis

Diagnosis Code E85.0

ICD-10: E85.0
Short Description: Non-neuropathic heredofamilial amyloidosis
Long Description: Non-neuropathic heredofamilial amyloidosis
This is the 2017 version of the ICD-10-CM diagnosis code E85.0

Code Classification
  • Endocrine, nutritional and metabolic diseases
    • Metabolic disorders (E70-E88)
      • Amyloidosis (E85)

Information for Medical Professionals

Diagnostic Related Groups
The diagnosis code E85.0 is grouped in the following Diagnostic Related Group(s) (MS-DRG v33.0)


Convert to ICD-9 Additional informationCallout TooltipGeneral Equivalence Map
The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.

  • Amyloid of familial Mediterranean fever
  • Familial Mediterranean fever
  • Familial non-neuropathic amyloidosis
  • Pericarditis associated with familial Mediterranean fever
  • Polyserositis

Index of Diseases and Injuries
References found for the code E85.0 in the Index of Diseases and Injuries:

Replaced Code Additional informationCallout TooltipReplaced Code
The National Center for Health Statistics (NCHS) has published an update to the ICD-10-CM diagnosis codes which became effective October 1, 2016. This codes was replaced for the FY 2017 (October 1, 2016-September 30, 2017).

This code was replaced in the 2017 ICD-10 code set with the code(s) listed below.
  • M04.1 - Periodic fever syndromes

Information for Patients


Amyloidosis occurs when abnormal proteins called amyloids build up and form deposits. The deposits can collect in organs such as the kidney and heart. This can cause the organs to become stiff and unable to work the way they should.

There are three main types of amyloidosis:

  • Primary - with no known cause
  • Secondary - caused by another disease, including some types of cancer
  • Familial - passed down through genes

Symptoms can vary, depending upon which organs are affected. Treatment depends on the type of amyloidosis you have. The goal is to help with symptoms and limit the production of proteins. If another disease is the cause, it needs to be treated.

  • Cardiac amyloidosis
  • Hereditary amyloidosis
  • Primary amyloidosis
  • Secondary systemic amyloidosis

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Familial Mediterranean fever Familial Mediterranean fever is an inherited condition characterized by recurrent episodes of painful inflammation in the abdomen, chest, or joints. These episodes are often accompanied by fever and sometimes a rash or headache. Occasionally inflammation may occur in other parts of the body, such as the heart; the membrane surrounding the brain and spinal cord; and in males, the testicles. In about half of affected individuals, attacks are preceded by mild signs and symptoms known as a prodrome. Prodromal symptoms include mildly uncomfortable sensations in the area that will later become inflamed, or more general feelings of discomfort.The first episode of illness in familial Mediterranean fever usually occurs in childhood or the teenage years, but in some cases, the initial attack occurs much later in life. Typically, episodes last 12 to 72 hours and can vary in severity. The length of time between attacks is also variable and can range from days to years. During these periods, affected individuals usually have no signs or symptoms related to the condition. However, without treatment to help prevent attacks and complications, a buildup of protein deposits (amyloidosis) in the body's organs and tissues may occur, especially in the kidneys, which can lead to kidney failure.
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