2024 ICD-10-CM Diagnosis Code E22.1

Hyperprolactinemia

ICD-10-CM Code:
E22.1
ICD-10 Code for:
Hyperprolactinemia
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Chronic
Code Navigator:

Code Classification

  • Endocrine, nutritional and metabolic diseases
    (E00–E89)
    • Disorders of other endocrine glands
      (E20-E35)
      • Hyperfunction of pituitary gland
        (E22)

E22.1 is a billable diagnosis code used to specify a medical diagnosis of hyperprolactinemia. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Drug-induced hyperprolactinemia
  • Familial hyperprolactinemia
  • Hyperprolactinemia
  • Hyperprolactinemia due to hypothyroidism
  • Idiopathic hyperprolactinemia
  • Lactation hyperprolactinemia
  • Macroprolactinemia
  • Physiological hyperprolactinemia
  • Physiological hyperprolactinemia
  • Pituitary stalk compression hyperprolactinemia
  • Pregnancy hyperprolactinemia
  • Secondary hyperprolactinemia
  • Secondary hyperprolactinemia
  • Secondary hyperprolactinemia
  • Secondary hyperprolactinemia due to prolactin-secreting tumor
  • Transient hyperprolactinemia

Clinical Classification

Clinical Information

  • Hyperprolactinemia

    increased levels of prolactin in the blood, which may be associated with amenorrhea and galactorrhea. relatively common etiologies include prolactinoma, medication effect, kidney failure, granulomatous diseases of the pituitary gland, and disorders which interfere with the hypothalamic inhibition of prolactin release. ectopic (non-pituitary) production of prolactin may also occur. (from joynt, clinical neurology, 1992, ch36, pp77-8)
  • Hyperprolactinemia

    abnormally high level of prolactin in the blood.

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.


Use Additional Code

Use Additional Code
The “use additional code” indicates that a secondary code could be used to further specify the patient’s condition. This note is not mandatory and is only used if enough information is available to assign an additional code.
  • code for adverse effect, if applicable, to identify drug T36 T50

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Convert E22.1 to ICD-9-CM

  • ICD-9-CM Code: 253.1 - Ant pituit hyperfunc NEC
    Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.

Patient Education


Pituitary Disorders

Your pituitary gland is a pea-sized gland at the base of your brain. The pituitary is the "master control gland" - it makes hormones that affect growth and the functions of other glands in the body.

With pituitary disorders, you often have too much or too little of one of your hormones. Injuries can cause pituitary disorders, but the most common cause is a pituitary tumor.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.