2024 ICD-10-CM Diagnosis Code D56.4

Hereditary persistence of fetal hemoglobin [HPFH]

ICD-10-CM Code:
D56.4
ICD-10 Code for:
Hereditary persistence of fetal hemoglobin [HPFH]
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Chronic
Code Navigator:

Code Classification

  • Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
    (D50–D89)

D56.4 is a billable diagnosis code used to specify a medical diagnosis of hereditary persistence of fetal hemoglobin [hpfh]. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • A>gamma< beta^+^ HPFH AND beta^0^ thalassemia in cis
  • Beta plus thalassemia
  • Beta plus thalassemia
  • Beta plus thalassemia
  • Beta zero thalassemia
  • Delta beta thalassemia
  • Delta beta zero thalassemia
  • Hereditary persistence of fetal hemoglobin
  • Hereditary persistence of fetal hemoglobin
  • Hereditary persistence of fetal hemoglobin delta beta plus thalassemia
  • Hereditary persistence of fetal hemoglobin G gamma beta plus thalassemia
  • Hereditary persistence of fetal hemoglobin thalassemia
  • Hereditary persistence of fetal hemoglobin thalassemia
  • Hereditary persistence of fetal hemoglobin thalassemia
  • Hereditary persistence of fetal hemoglobin thalassemia
  • Hereditary persistence of fetal hemoglobin with sickle cell disease syndrome
  • HPFH A gamma beta^+^ thalassemia
  • HPFH deletion type
  • HPFH linked to beta-globulin gene cluster
  • HPFH nondeletion type
  • HPFH unlinked to beta-globulin gene cluster

Clinical Classification

Clinical Information

  • Hereditary Persistence of Fetal Hemoglobin

    the persistence of substantial fetal hemoglobin production into adulthood, usually associated with hemoglobinopathies due to mutations in the alpha and/or beta chain of hemoglobin.

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Convert D56.4 to ICD-9-CM

  • ICD-9-CM Code: 282.7 - Hemoglobinopathies NEC
    Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.

Patient Education


Thalassemia

Thalassemias are inherited blood disorders. If you have one, your body makes fewer healthy red blood cells and less hemoglobin. Hemoglobin is a protein that carries oxygen to the body. That leads to anemia. Thalassemias occur most often among people of Italian, Greek, Middle Eastern, Southern Asian, and African descent.

Thalassemias can be mild or severe. Some people have no symptoms or mild anemia. The most common severe type in the United States is called Cooley's anemia. It usually appears during the first two years of life. People with it may have severe anemia, slowed growth and delayed puberty, and problems with the spleen, liver, heart, or bones.

Doctors diagnose thalassemias using blood tests. Treatments include blood transfusions and treatment to remove excess iron from the body. If you have mild symptoms or no symptoms, you may not need treatment. In some severe cases, you may need a bone marrow transplant.

NIH: National Heart, Lung, and Blood Institute


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.