2024 ICD-10-CM Diagnosis Code D35.00

Benign neoplasm of unspecified adrenal gland

ICD-10-CM Code:
D35.00
ICD-10 Code for:
Benign neoplasm of unspecified adrenal gland
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Not chronic
Code Navigator:

Code Classification

  • Neoplasms
    (C00–D49)
    • Benign neoplasms, except benign neuroendocrine tumors
      (D10-D36)
      • Benign neoplasm of other and unspecified endocrine glands
        (D35)

D35.00 is a billable diagnosis code used to specify a medical diagnosis of benign neoplasm of unspecified adrenal gland. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

The following anatomical sites found in the Table of Neoplasms reference the parent code D35.0 of the current diagnosis code given the correct histological behavior: Neoplasm, neoplastic adrenal ; Neoplasm, neoplastic adrenal capsule ; Neoplasm, neoplastic adrenal cortex ; Neoplasm, neoplastic adrenal gland ; Neoplasm, neoplastic adrenal medulla ; Neoplasm, neoplastic cortex ; Neoplasm, neoplastic cortex adrenal ; etc

Unspecified diagnosis codes like D35.00 are acceptable when clinical information is unknown or not available about a particular condition. Although a more specific code is preferable, unspecified codes should be used when such codes most accurately reflect what is known about a patient's condition. Specific diagnosis codes should not be used if not supported by the patient's medical record.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Adrenal adenoma
  • Adrenal adenoma
  • Adrenal cortical adenoma
  • Adrenal cortical adenoma
  • Aldosterone-producing adenoma
  • Benign neoplasm of adrenal cortex
  • Benign neoplasm of adrenal cortex
  • Benign neoplasm of adrenal gland
  • Benign neoplasm of adrenal medulla
  • Benign pheochromocytoma
  • Hereditary pheochromocytoma and paraganglioma
  • Hyperaldosteronism due to neoplasm of the adrenal cortex
  • Hypermelanosis due to neoplasia
  • Hypermelanosis due to pheochromocytoma
  • Myelolipoma of adrenal gland
  • Paraganglioma
  • Paraganglioma
  • Pheochromocytoma
  • Pheochromocytoma crisis
  • Primary hyperaldosteronism due to adrenal adenoma
  • Sporadic pheochromocytoma and secreting paraganglioma
  • Tremor due to pheochromocytoma

Clinical Classification

Clinical Information

  • Carotid Body Tumor

    benign paraganglioma at the bifurcation of the common carotid arteries. it can encroach on the parapharyngeal space and produce dysphagia, pain, and cranial nerve palsies.
  • Glomus Jugulare Tumor

    a paraganglioma involving the glomus jugulare, a microscopic collection of chemoreceptor tissue in the adventitia of the bulb of the jugular vein. it may cause paralysis of the vocal cords, attacks of dizziness, blackouts, and nystagmus. it is not resectable but radiation therapy is effective. it regresses slowly, but permanent control is regularly achieved. (from dorland, 27th ed; stedman, 25th ed; devita jr et al., cancer: principles & practice of oncology, 3d ed, pp1603-4)
  • Paraganglioma

    a neural crest tumor usually derived from the chromoreceptor tissue of a paraganglion, such as the carotid body, or medulla of the adrenal gland (usually called a chromaffinoma or pheochromocytoma). it is more common in women than in men. (stedman, 25th ed; from segen, dictionary of modern medicine, 1992)
  • Paraganglioma, Extra-Adrenal

    a relatively rare, usually benign neoplasm originating in the chemoreceptor tissue of the carotid body; glomus jugulare; glomus tympanicum; aortic bodies; and the female genital tract. it consists histologically of rounded or ovoid hyperchromatic cells that tend to be grouped in an alveolus-like pattern within a scant to moderate amount of fibrous stroma and a few large thin-walled vascular channels. (from stedman, 27th ed)
  • Multiple Endocrine Neoplasia Type 2a

    a form of multiple endocrine neoplasia characterized by the presence of medullary carcinoma (carcinoma, medullary) of the thyroid gland, and usually with the co-occurrence of pheochromocytoma, producing calcitonin and adrenaline, respectively. less frequently, it can occur with hyperplasia or adenoma of the parathyroid glands. this disease is due to gain-of-function mutations of the men2 gene on chromosome 10 (locus: 10q11.2), also known as the ret proto-oncogene that encodes a receptor protein-tyrosine kinase. it is an autosomal dominant inherited disease.
  • PC12 Cells

    a cell line derived from a pheochromocytoma of the rat adrenal medulla. pc12 cells stop dividing and undergo terminal differentiation when treated with nerve growth factor, making the line a useful model system for nerve cell differentiation.
  • Pheochromocytoma

    a usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the adrenal medulla or sympathetic paraganglia. the cardinal symptom, reflecting the increased secretion of epinephrine and norepinephrine, is hypertension, which may be persistent or intermittent. during severe attacks, there may be headache; sweating, palpitation, apprehension, tremor; pallor or flushing of the face, nausea and vomiting, pain in the chest and abdomen, and paresthesias of the extremities. the incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (dorland, 27th ed; devita jr et al., cancer: principles & practice of oncology, 3d ed, p1298)
  • Carotid Artery, Common

    the two principal arteries supplying the structures of the head and neck. they ascend in the neck, one on each side, and at the level of the upper border of the thyroid cartilage, each divides into two branches, the external (carotid artery, external) and internal (carotid artery, internal) carotid arteries.

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Convert D35.00 to ICD-9-CM

  • ICD-9-CM Code: 227.0 - Benign neoplasm adrenal
    Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.

Table of Neoplasms

The parent code D35.0 of the current diagnosis code is referenced in the table of neoplasms by anatomical site. For each site there are six possible code numbers according to whether the neoplasm in question is malignant, benign, in situ, of uncertain behavior, or of unspecified nature. The description of the neoplasm will often indicate which of the six columns is appropriate.

Where such descriptors are not present, the remainder of the Index should be consulted where guidance is given to the appropriate column for each morphological (histological) variety listed. However, the guidance in the Index can be overridden if one of the descriptors mentioned above is present.

Neoplasm, neoplastic Malignant
Primary
Malignant
Secondary
CaInSitu Benign Uncertain
Behavior
Unspecified
Behavior
»Neoplasm, neoplastic
  »adrenal
C74.9C79.7D09.3D35.0D44.1D49.7
»Neoplasm, neoplastic
  »adrenal
    »capsule
C74.9C79.7D09.3D35.0D44.1D49.7
»Neoplasm, neoplastic
  »adrenal
    »cortex
C74.0C79.7D09.3D35.0D44.1D49.7
»Neoplasm, neoplastic
  »adrenal
    »gland
C74.9C79.7D09.3D35.0D44.1D49.7
»Neoplasm, neoplastic
  »adrenal
    »medulla
C74.1C79.7D09.3D35.0D44.1D49.7
»Neoplasm, neoplastic
  »cortex
C74.0C79.7D09.3D35.0D44.1D49.7
»Neoplasm, neoplastic
  »cortex
    »adrenal
C74.0C79.7D09.3D35.0D44.1D49.7
»Neoplasm, neoplastic
  »medulla
C74.1C79.7D09.3D35.0D44.1D49.7
»Neoplasm, neoplastic
  »medulla
    »adrenal
C74.1C79.7D09.3D35.0D44.1D49.7
»Neoplasm, neoplastic
  »suprarenal
C74.9C79.7D09.3D35.0D44.1D49.7
»Neoplasm, neoplastic
  »suprarenal
    »capsule
C74.9C79.7D09.3D35.0D44.1D49.7
»Neoplasm, neoplastic
  »suprarenal
    »cortex
C74.0C79.7D09.3D35.0D44.1D49.7
»Neoplasm, neoplastic
  »suprarenal
    »gland
C74.9C79.7D09.3D35.0D44.1D49.7
»Neoplasm, neoplastic
  »suprarenal
    »medulla
C74.1C79.7D09.3D35.0D44.1D49.7

Patient Education


Adrenal Gland Disorders

What are adrenal glands?

Your adrenal glands are two small organs that sit on top of each kidney. The adrenal glands make different types of hormones you need to stay alive and healthy. Hormones are chemicals that travel in your bloodstream and control how different parts of your body work.

The adrenal glands make the hormones cortisol, aldosterone, adrenaline, and noradrenaline. They also make hormones that your body uses to make sex hormones (estrogen and testosterone). All of these hormones do many important jobs, including:

  • Turning food into energy and managing blood sugar levels
  • Balancing salt and water
  • Keeping blood pressure normal
  • Responding to illness and stress (your "fight or flight" response)
  • Timing when and how fast a child develops sexually
  • Supporting pregnancy

What are adrenal gland disorders?

When you have an adrenal gland disorder, your body makes too much or too little of one or more hormones. The symptoms depend on the type of problem you have and how much it affects the hormone levels in your body.

There are many types of adrenal gland disorders, including:

  • Addison's Disease - a condition in which the adrenal glands don't make enough cortisol
  • Cushing's Syndrome - a condition caused by too much cortisol in the body, often from taking steroid medicines for a long time
  • Aldosterone-producing adenoma - a benign tumor (not cancer) that makes too much aldosterone and may cause serious high blood pressure
  • Hereditary paraganglioma-pheochromocytoma - an inherited condition causing different types of tumors that make adrenaline and other hormones. Some tumors may become cancerous.
  • Adrenal gland cancer - cancerous tumors, including adrenocortical carcinoma and neuroblastoma
  • Congenital Adrenal Hyperplasia (CAH) - a group of inherited disorders in which the adrenal glands don't make enough cortisol. The most common type is 21-hydroxylase deficiency (also called CAH1). In the United States, newborn babies get a blood test to see if they have CAH. People born with CAH may not have symptoms until childhood or later in life.

What causes adrenal gland disorders?

The cause of adrenal gland disorders depends on the type of disorder you have. Causes can include:

  • Medicines such as steroids
  • A problem in another gland, such as the pituitary gland. The pituitary gland releases hormones that affect how the adrenal glands work.
  • Changes in genes (mutations). These changes can cause the adrenal glands to make too much or too little of one or more hormones.
  • Infections

In many cases the cause of the problem isn't clear.

How are adrenal gland disorders diagnosed?

Health care providers use different tests to check for adrenal disorders depending on your symptoms and health history. For example, you may have tests of your blood, urine (pee), or saliva (spit). These tests check your hormone levels. Your provider may order x-rays, CT scans, or MRI scans to look for tumors.

What are the treatments for adrenal gland disorders?

Different types of adrenal gland disorders have different treatments. They include medicines and surgery. Radiation therapy is sometimes a treatment for tumors. There are treatments to cure certain adrenal gland disorders. For other disorders, treatments can manage your symptoms.

NIH: National Institute of Child Health and Human Development


[Learn More in MedlinePlus]

Benign Tumors

Tumors are abnormal growths in your body. They can be either benign or malignant. Benign tumors aren't cancer. Malignant ones are. Benign tumors grow only in one place. They cannot spread or invade other parts of your body. Even so, they can be dangerous if they press on vital organs, such as your brain.

Tumors are made up of extra cells. Normally, cells grow and divide to form new cells as your body needs them. When cells grow old, they die, and new cells take their place. Sometimes, this process goes wrong. New cells form when your body does not need them, and old cells do not die when they should. These extra cells can divide without stopping and may form tumor.

Treatment often involves surgery. Benign tumors usually don't grow back.

NIH: National Cancer Institute


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.