ICD-10 Diagnosis Code C49.9

Malignant neoplasm of connective and soft tissue, unsp

Diagnosis Code C49.9

ICD-10: C49.9
Short Description: Malignant neoplasm of connective and soft tissue, unsp
Long Description: Malignant neoplasm of connective and soft tissue, unspecified
This is the 2017 version of the ICD-10-CM diagnosis code C49.9

Valid for Submission
The code C49.9 is valid for submission for HIPAA-covered transactions.

Code Classification
  • Neoplasms (C00–D48)
    • Malignant neoplasms of mesothelial and soft tissue (C45-C49)
      • Malignant neoplasm of other connective and soft tissue (C49)

Information for Medical Professionals

Diagnostic Related Groups
The diagnosis code C49.9 is grouped in the following Diagnostic Related Group(s) (MS-DRG v33.0)


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The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.

  • Adipocytic liposarcoma
  • Alveolar rhabdomyosarcoma
  • Alveolar soft part sarcoma
  • Angiosarcoma
  • Botryoid rhabdomyosarcoma
  • Cutaneous fibrosarcoma
  • Cutaneous leiomyosarcoma
  • Cutaneous leiomyosarcoma with granular cell change
  • Dedifferentiated liposarcoma
  • Embryonal rhabdomyosarcoma
  • Epithelioid leiomyosarcoma of skin
  • Ewing's sarcoma of soft tissue
  • Extraskeletal osteosarcoma
  • Fibrosarcoma of connective tissue
  • Giant cell malignant fibrous histiocytoma of skin
  • Infantile fibrosarcoma
  • Inflammatory malignant fibrous histiocytoma of skin
  • Intravascular angiosarcoma
  • Leiomyosarcoma
  • Leiomyosarcoma of connective tissue
  • Liposarcoma
  • Liposarcoma of connective tissue
  • Local recurrence of malignant tumor of soft tissue
  • Low-grade fibromyxoid sarcoma
  • Lymphangiosarcoma
  • Malignant fibrohistiocytic tumor of skin
  • Malignant fibromatous neoplasm
  • Malignant fibrous histiocytoma
  • Malignant fibrous histiocytoma of skin
  • Malignant granular cell tumor
  • Malignant melanoma of soft tissues
  • Malignant neoplasm of bone, connective tissue, skin and breast
  • Malignant neoplasm of connective tissue
  • Malignant neoplasm of soft tissue
  • Malignant neoplasm of subcutaneous fibrous tissue
  • Malignant tumor of dermis
  • Malignant tumor of fibrous tissue
  • Malignant tumor of muscle
  • Malignant tumor of nerve sheath origin
  • Metastasis from malignant tumor of soft tissues
  • Myxofibrosarcoma of skin
  • Myxoid leiomyosarcoma of skin
  • Myxoid liposarcoma
  • Pleomorphic liposarcoma
  • Pleomorphic malignant fibrous histiocytoma of skin
  • Pleomorphic rhabdomyosarcoma
  • Primary leiomyosarcoma
  • Primary malignant neoplasm of blood vessel
  • Primary malignant neoplasm of muscle
  • Primary malignant neoplasm of soft tissues
  • Rhabdomyosarcoma
  • Rhabdomyosarcoma of connective or soft tissue
  • Round cell liposarcoma
  • Sarcoma
  • Sarcoma of bone and connective tissue
  • Sarcoma of connective tissue
  • Sarcoma of soft tissue
  • Sclerosing liposarcoma
  • Spindle cell liposarcoma
  • Spindle cell rhabdomyosarcoma
  • Superficial malignant fibrous histiocytoma of skin
  • Synovial sarcoma
  • Synovial-like neoplasm
  • Vaccine-induced fibrosarcoma

Information for Patients


Also called: Carcinoma, Malignancy, Neoplasms, Tumor

Cancer begins in your cells, which are the building blocks of your body. Normally, your body forms new cells as you need them, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor. Tumors can be benign or malignant. Benign tumors aren't cancer while malignant ones are. Cells from malignant tumors can invade nearby tissues. They can also break away and spread to other parts of the body.

Cancer is not just one disease but many diseases. There are more than 100 different types of cancer. Most cancers are named for where they start. For example, lung cancer starts in the lung, and breast cancer starts in the breast. The spread of cancer from one part of the body to another is called metastasis. Symptoms and treatment depend on the cancer type and how advanced it is. Most treatment plans may include surgery, radiation and/or chemotherapy. Some may involve hormone therapy, biologic therapy, or stem cell transplantation.

NIH: National Cancer Institute

  • Cancer
  • Cancer and lymph nodes
  • Cancer prevention: take charge of your lifestyle
  • Cancer treatment -- early menopause
  • Cancer treatment: preventing infection
  • Cancer treatments
  • Hyperthermia for treating cancer
  • Laser therapy for cancer
  • Photodynamic therapy for cancer
  • Targeted therapies for cancer

[Read More]

Connective Tissue Disorders

Connective tissue is the material inside your body that supports many of its parts. It is the "cellular glue" that gives your tissues their shape and helps keep them strong. It also helps some of your tissues do their work. Cartilage and fat are examples of connective tissue.

There are over 200 disorders that impact connective tissue. Some, like cellulitis, are the result of an infection. Injuries can cause connective tissue disorders, such as scars. Others, such as Ehlers-Danlos syndrome, Marfan syndrome, and osteogenesis imperfecta, are genetic. Still others, like scleroderma, have no known cause. Each disorder has its own symptoms and needs different treatment.

  • Dupuytrens contracture

[Read More]
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