ICD-10 Diagnosis Code A81.2

Progressive multifocal leukoencephalopathy

Diagnosis Code A81.2

ICD-10: A81.2
Short Description: Progressive multifocal leukoencephalopathy
Long Description: Progressive multifocal leukoencephalopathy
This is the 2017 version of the ICD-10-CM diagnosis code A81.2

Code Classification
  • Certain infectious and parasitic diseases
    • Viral and prion infections of the central nervous system (A80-A89)
      • Atypical virus infections of central nervous system (A81)

Information for Medical Professionals

Convert to ICD-9 Additional informationCallout TooltipGeneral Equivalence Map
The ICD-10 and ICD-9 GEMs are used to facilitate linking between the diagnosis codes in ICD-9-CM and the new ICD-10-CM code set. The GEMs are the raw material from which providers, health information vendors and payers can derive specific applied mappings to meet their needs.

  • Central nervous system demyelinating disease associated with acquired immunodeficiency syndrome
  • Cerebral degeneration due to progressive multifocal leukoencephalopathy
  • Disease caused by JC polyomavirus
  • Disease caused by JC polyomavirus
  • Disease caused by Polyomaviridae
  • Disease caused by Polyomaviridae
  • Disease caused by Polyomavirus
  • Disease caused by Polyomavirus
  • Encephalopathy associated with acquired immunodeficiency syndrome
  • Leukoencephalopathy with brainstem and spinal cord involvement and lactate elevation
  • Progressive multifocal leukoencephalopathy
  • Progressive multifocal leukoencephalopathy
  • Progressive multifocal leukoencephalopathy associated with acquired immunodeficiency syndrome

Index of Diseases and Injuries
References found for the code A81.2 in the Index of Diseases and Injuries:

Information for Patients

Degenerative Nerve Diseases

Also called: Neurodegenerative diseases

Degenerative nerve diseases affect many of your body's activities, such as balance, movement, talking, breathing, and heart function. Many of these diseases are genetic. Sometimes the cause is a medical condition such as alcoholism, a tumor, or a stroke. Other causes may include toxins, chemicals, and viruses. Sometimes the cause is not known.

Degenerative nerve diseases include

  • Alzheimer's disease
  • Amyotrophic lateral sclerosis
  • Friedreich's ataxia
  • Huntington's disease
  • Lewy body disease
  • Parkinson's disease
  • Spinal muscular atrophy

Degenerative nerve diseases can be serious or life-threatening. It depends on the type. Most of them have no cure. Treatments may help improve symptoms, relieve pain, and increase mobility.

  • Multiple system atrophy
  • Progressive multifocal leukoencephalopathy

[Read More]


Encephalitis is an inflammation of the brain. Usually the cause is a viral infection, but bacteria can also cause it. It can be mild or severe. Most cases are mild. You may have flu-like symptoms. With a mild case, you may just need rest, plenty of fluids, and a pain reliever.

Severe cases need immediate treatment. Symptoms of severe cases include

  • Severe headache
  • Sudden fever
  • Drowsiness
  • Vomiting
  • Confusion
  • Seizures

In babies, additional symptoms may include constant crying, poor feeding, body stiffness, and bulging in the soft spots of the skull.

Severe cases may require a stay in the hospital. Treatments include oral and intravenous (IV) medicines to reduce inflammation and treat infection. Patients with breathing difficulties may need artificial respiration. Some people may need physical, speech, and occupational therapy once the illness is under control.

NIH: National Institute of Neurological Disorders and Stroke

  • Cerebral spinal fluid (CSF) collection
  • CSF analysis
  • Encephalitis
  • Japanese Encephalitis Vaccine: What You Need to Know (Centers for Disease Control and Prevention)
  • Subacute sclerosing panencephalitis

[Read More]

Viral Infections

Viruses are capsules with genetic material inside. They are very tiny, much smaller than bacteria. Viruses cause familiar infectious diseases such as the common cold, flu and warts. They also cause severe illnesses such as HIV/AIDS, smallpox and hemorrhagic fevers.

Viruses are like hijackers. They invade living, normal cells and use those cells to multiply and produce other viruses like themselves. This eventually kills the cells, which can make you sick.

Viral infections are hard to treat because viruses live inside your body's cells. They are "protected" from medicines, which usually move through your bloodstream. Antibiotics do not work for viral infections. There are a few antiviral medicines available. Vaccines can help prevent you from getting many viral diseases.

NIH: National Institute of Allergy and Infectious Diseases

  • ECHO virus
  • Enterovirus D68
  • Hand-foot-mouth disease
  • Herpangina
  • Molluscum contagiosum
  • Parainfluenza
  • Roseola
  • Zika virus disease

[Read More]
Previous Code
Previous Code A81.1
Next Code
A81.8 Next Code