2024 ICD-10-CM Diagnosis Code Z15.89
Genetic susceptibility to other disease
- ICD-10-CM Code:
- Z15.89
- ICD-10 Code for:
- Genetic susceptibility to other disease
- Is Billable?
- Yes - Valid for Submission
- Code Navigator:
Z15.89 is a billable diagnosis code used to specify a medical diagnosis of genetic susceptibility to other disease. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024. The code is exempt from present on admission (POA) reporting for inpatient admissions to general acute care hospitals.
This code describes a circumstance which influences the patient's health status but not a current illness or injury. The code is unacceptable as a principal diagnosis.
Approximate Synonyms
The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:
- Autosomal dominant mendelian susceptibility to mycobacterial disease due to partial interferon gamma receptor 1 deficiency
- Autosomal dominant mendelian susceptibility to mycobacterial disease due to partial interferon gamma receptor 2 deficiency
- Autosomal recessive mendelian susceptibility to mycobacterial disease due to complete RORgamma receptor mutation
- Autosomal recessive mendelian susceptibility to mycobacterial disease due to partial interferon gamma receptor 2 deficiency
- Dense body defect
- Familial platelet syndrome with predisposition to acute myelogenous leukemia
- Genetic susceptibility to genetic disorder
- Genetic susceptibility to genetic disorder
- Genetic susceptibility to malignant hyperthermia due to calcium voltage-gated channel subunit alpha1 S gene mutation
- Genetic susceptibility to malignant hyperthermia due to ryanodine receptor 1 gene mutation
- Malignant hyperthermia genetic susceptibility
- Malignant hyperthermia genetic susceptibility
- Mendelian susceptibility to mycobacterial disease
- Mendelian susceptibility to mycobacterial disease due to complete IL12RB1 deficiency
- Mendelian susceptibility to mycobacterial disease due to complete interferon gamma receptor 1 deficiency
- Mendelian susceptibility to mycobacterial disease due to complete interferon gamma receptor 2 deficiency
- Mendelian susceptibility to mycobacterial disease due to complete interleukin 12 subunit beta deficiency
- Mendelian susceptibility to mycobacterial disease due to complete ISG15 deficiency
- Mendelian susceptibility to mycobacterial disease due to partial IRF8 deficiency
- Mendelian susceptibility to mycobacterial disease due to partial STAT1 deficiency
- Predisposition to invasive fungal disease due to CARD9 deficiency
- Susceptibility to infection due to TYK2 deficiency
- Uncertain genetic susceptibility to malignant hyperthermia due to CACNA1S gene mutation
- Uncertain malignant hyperthermia predisposition due to RyR1 gene mutation
- X-linked mendelian susceptibility to mycobacterial disease
Clinical Classification
Clinical Category is Personal/family history of disease
- CCSR Category Code: FAC021
- Inpatient Default CCSR: X - Not applicable.
- Outpatient Default CCSR: X - Not applicable.
Index to Diseases and Injuries References
The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).
- - Genetic
- - susceptibility to disease NEC - Z15.89
- - Susceptibility to disease, genetic - Z15.89
Code Edits
The Medicare Code Editor (MCE) detects and reports errors in the coding of claims data. The following ICD-10-CM Code Edits are applicable to this code:
- Unacceptable principal diagnosis - There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.
Present on Admission (POA)
Z15.89 is exempt from POA reporting - The Present on Admission (POA) indicator is used for diagnosis codes included in claims involving inpatient admissions to general acute care hospitals. POA indicators must be reported to CMS on each claim to facilitate the grouping of diagnoses codes into the proper Diagnostic Related Groups (DRG). CMS publishes a listing of specific diagnosis codes that are exempt from the POA reporting requirement. Review other POA exempt codes here.
CMS POA Indicator Options and Definitions
| POA Indicator | Reason for Code | CMS will pay the CC/MCC DRG? |
|---|---|---|
| Y | Diagnosis was present at time of inpatient admission. | YES |
| N | Diagnosis was not present at time of inpatient admission. | NO |
| U | Documentation insufficient to determine if the condition was present at the time of inpatient admission. | NO |
| W | Clinically undetermined - unable to clinically determine whether the condition was present at the time of inpatient admission. | YES |
| 1 | Unreported/Not used - Exempt from POA reporting. | NO |
Convert Z15.89 to ICD-9-CM
- ICD-9-CM Code: V84.89 - Genetic suscept dis NEC
Code History
- FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
- FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
- FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
- FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
- FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
- FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
- FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
- FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
- FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.