2024 ICD-10-CM Diagnosis Code Z15.09

Genetic susceptibility to other malignant neoplasm

ICD-10-CM Code:
Z15.09
ICD-10 Code for:
Genetic susceptibility to other malignant neoplasm
Is Billable?
Yes - Valid for Submission
Code Navigator:

Code Classification

  • Factors influencing health status and contact with health services
    (Z00–Z99)
    • Genetic carrier and genetic susceptibility to disease
      (Z14-Z15)
      • Genetic susceptibility to disease
        (Z15)

Z15.09 is a billable diagnosis code used to specify a medical diagnosis of genetic susceptibility to other malignant neoplasm. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024. The code is exempt from present on admission (POA) reporting for inpatient admissions to general acute care hospitals.

This code describes a circumstance which influences the patient's health status but not a current illness or injury. The code is unacceptable as a principal diagnosis.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • BAP1 tumor predisposition syndrome
  • Combined immunodeficiency due to CARMIL2 deficiency
  • Combined immunodeficiency due to CD70 deficiency
  • DDX41-related hematologic malignancy predisposition syndrome
  • DICER1 syndrome
  • Familial cutaneous telangiectasia and oropharyngeal cancer predisposition syndrome
  • Genetic susceptibility to cancer
  • Hereditary cancer-predisposing syndrome
  • Hereditary non-polyposis colon cancer gene mutation detected
  • Inherited cancer-predisposing syndrome due to biallelic BRCA2 mutation
  • Lynch syndrome
  • Macroencephaly
  • Megalencephaly capillary malformation
  • MITF-related melanoma and renal cell carcinoma predisposition syndrome
  • Mosaic variegated aneuploidy syndrome
  • Oligodontia
  • Oligodontia and cancer predisposition syndrome
  • Palmoplantar keratoderma, 46,XX sex reversal, predisposition to squamous cell carcinoma syndrome
  • Progeroid features, hepatocellular carcinoma predisposition syndrome
  • Rhabdoid tumor predisposition syndrome

Clinical Classification

Clinical Information

  • DICER1 Syndrome

    a rare, autosomal dominant inherited syndrome caused by mutations in the dicer1 gene. people with this syndrome are at an increased risk of developing pleuropulmonary blastoma, cystic nephroma, sertoli-leydig cell tumor of the ovary, and multinodular goiter.

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Code Edits

The Medicare Code Editor (MCE) detects and reports errors in the coding of claims data. The following ICD-10-CM Code Edits are applicable to this code:

  • Unacceptable principal diagnosis - There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Present on Admission (POA)

Z15.09 is exempt from POA reporting - The Present on Admission (POA) indicator is used for diagnosis codes included in claims involving inpatient admissions to general acute care hospitals. POA indicators must be reported to CMS on each claim to facilitate the grouping of diagnoses codes into the proper Diagnostic Related Groups (DRG). CMS publishes a listing of specific diagnosis codes that are exempt from the POA reporting requirement. Review other POA exempt codes here.

CMS POA Indicator Options and Definitions

POA IndicatorReason for CodeCMS will pay the CC/MCC DRG?
YDiagnosis was present at time of inpatient admission.YES
NDiagnosis was not present at time of inpatient admission.NO
UDocumentation insufficient to determine if the condition was present at the time of inpatient admission.NO
WClinically undetermined - unable to clinically determine whether the condition was present at the time of inpatient admission.YES
1Unreported/Not used - Exempt from POA reporting. NO

Convert Z15.09 to ICD-9-CM

  • ICD-9-CM Code: V84.09 - Genetic susc mal neo NEC

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.