2024 ICD-10-CM Diagnosis Code T50.6X6A

Underdosing of antidotes and chelating agents, initial encounter

ICD-10-CM Code:
T50.6X6A
ICD-10 Code for:
Underdosing of antidotes and chelating agents, init encntr
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Not chronic
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances
        (T50)

T50.6X6A is a billable diagnosis code used to specify a medical diagnosis of underdosing of antidotes and chelating agents, initial encounter. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

This code describes a circumstance which influences the patient's health status but not a current illness or injury. The code is unacceptable as a principal diagnosis.

T50.6X6A is an initial encounter code, includes a 7th character and should be used while the patient is receiving active treatment for a condition like underdosing of antidotes and chelating agents. According to ICD-10-CM Guidelines an "initial encounter" doesn't necessarily means "initial visit". The 7th character should be used when the patient is undergoing active treatment regardless if new or different providers saw the patient over the course of a treatment. The appropriate 7th character codes should also be used even if the patient delayed seeking treatment for a condition.

Clinical Classification

Clinical Information

  • Cysteamine

    a mercaptoethylamine compound that is endogenously derived from the coenzyme a degradative pathway. the fact that cysteamine is readily transported into lysosomes where it reacts with cystine to form cysteine-cysteamine disulfide and cysteine has led to its use in cystine depleting agents for the treatment of cystinosis.
  • Disulfiram

    a carbamate derivative used as an alcohol deterrent. it is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. when alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). it acts by inhibiting aldehyde dehydrogenase.
  • Glutathione

    a tripeptide with many roles in cells. it conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.
  • Glutathione Disulfide

    a glutathione dimer formed by a disulfide bond between the cysteine sulfhydryl side chains during the course of being oxidized.
  • Glutathione Peroxidase

    an enzyme catalyzing the oxidation of 2 moles of glutathione in the presence of hydrogen peroxide to yield oxidized glutathione and water.
  • Glutathione Peroxidase GPX1

    one of the most abundant isoenzymes of the glutathione peroxidase family. located in the cytosol and mitochondria, it catalyzes the reduction of hydrogen peroxide to water, functioning to limit the accumulation of hydrogen peroxide and modulating processes that utilize hydrogen peroxide; and also the reduction of other organic hydroperoxides to their corresponding alcohols.
  • Glutathione Reductase

    catalyzes the oxidation of glutathione to glutathione disulfide in the presence of nadp+. deficiency in the enzyme is associated with hemolytic anemia. formerly listed as ec 1.6.4.2.
  • Glutathione S-Transferase pi

    a glutathione transferase that catalyzes the conjugation of electrophilic substrates to glutathione. this enzyme has been shown to provide cellular protection against redox-mediated damage by free radicals.
  • Glutathione Synthase

    one of the enzymes active in the gamma-glutamyl cycle. it catalyzes the synthesis of glutathione from gamma-glutamylcysteine and glycine in the presence of atp with the formation of adp and orthophosphate. ec 6.3.2.3.
  • Glutathione Transferase

    a transferase that catalyzes the addition of aliphatic, aromatic, or heterocyclic free radicals as well as epoxides and arene oxides to glutathione. addition takes place at the sulfur. it also catalyzes the reduction of polyol nitrate by glutathione to polyol and nitrite.
  • Lactoylglutathione Lyase

    an enzyme that catalyzes the interconversion of methylglyoxal and lactate, with glutathione serving as a coenzyme. ec 4.4.1.5.
  • Phospholipid Hydroperoxide Glutathione Peroxidase

    a selenoenzyme that converts glutathione plus fatty acid hydroperoxides to glutathione disulfide plus hydroxy fatty acids and water.
  • Protein Disulfide Reductase (Glutathione)

    an enzyme that catalyzes the reduction of a protein-disulfide in the presence of glutathione, forming a protein-dithiol. insulin is one of its substrates. ec 1.8.4.2.
  • Obidoxime Chloride

    cholinesterase reactivator occurring in two interchangeable isomeric forms, syn and anti.
  • Penicillamine

    3-mercapto-d-valine. the most characteristic degradation product of the penicillin antibiotics. it is used as an antirheumatic and as a chelating agent in wilson's disease.

Coding Guidelines

Underdosing refers to taking less of a medication than is prescribed by a provider or a manufacturer's instruction. Codes for underdosing should never be assigned as principal or first-listed codes. If a patient has a relapse or exacerbation of the medical condition for which the drug is prescribed because of the reduction in dose, then the medical condition itself should be coded.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances (T50). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Code Edits

The Medicare Code Editor (MCE) detects and reports errors in the coding of claims data. The following ICD-10-CM Code Edits are applicable to this code:

  • Unacceptable principal diagnosis - There are selected codes that describe a circumstance which influences an individual's health status but not a current illness or injury, or codes that are not specific manifestations but may be due to an underlying cause. These codes are considered unacceptable as a principal diagnosis.

Convert T50.6X6A to ICD-9-CM

  • ICD-9-CM Code: -
    No Map Flag -

Table of Drugs and Chemicals

The parent code T50.6X6 of the current diagnosis code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
(self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AntabuseT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Antidote NECT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Antidote NEC
  »heavy metal
T50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Chelating agent NECT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Cholinesterase reactivatorT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
CysteamineT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Deterrent, alcoholT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Detoxifying agentT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Disodium edetateT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
DisulfiramT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
EDTAT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Ethylenediaminetetra-acetic acidT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Ethylenedinitrilotetra-acetateT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Fytic acid, nonasodiumT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
GlutathioneT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
MethyleneT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Methylene
  »blue
T50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Methylene
  »chloride or dichloride (solvent) NEC
T50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Methylthionine chlorideT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Methylthioninium chlorideT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
NitrefazoleT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Obidoxime chlorideT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
PAM (pralidoxime)T50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
PenicillamineT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Pralidoxime (iodide)T50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Pralidoxime (iodide)
  »chloride
T50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
ProtopamT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Tetraethylthiuram disulfideT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
Trisodium hydrogen edetateT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6
VersenateT50.6X1T50.6X2T50.6X3T50.6X4T50.6X5T50.6X6

Patient Education


Medication Errors

Medicines treat infectious diseases, prevent problems from chronic diseases, and ease pain. But medicines can also cause harmful reactions if not used correctly. Errors can happen in the hospital, at the health care provider's office, at the pharmacy, or at home. You can help prevent errors by:

  • Knowing your medicines. When you get a prescription, ask the name of the medicine and check to make sure that the pharmacy gave you the right medicine. Make sure that you understand how often you should take the medicine and how long you should take it.
  • Keeping a list of medicines.
    • Write down all of the medicines that you are taking, including the names of your medicines, how much you take, and when you take them. Make sure to include any over-the-counter medicines, vitamins, supplements, and herbs that you take.
    • List the medicines that you are allergic to or that have caused you problems in the past.
    • Take this list with you every time you see a health care provider.
  • Reading medicine labels and following the directions. Don't just rely on your memory - read the medication label every time. Be especially careful when giving medicines to children.
  • Asking questions. If you don't know the answers to these questions, ask your health care provider or pharmacist:
    • Why am I taking this medicine?
    • What are the common side effects?
    • What should I do if I have side effects?
    • When should I stop this medicine?
    • Can I take this medicine with the other medicines and supplements on my list?
    • Do I need to avoid certain foods or alcohol while taking this medicine?

Food and Drug Administration


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Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

Footnotes

[1] Not chronic - A diagnosis code that does not fit the criteria for chronic condition (duration, ongoing medical treatment, and limitations) is considered not chronic. Some codes designated as not chronic are acute conditions. Other diagnosis codes that indicate a possible chronic condition, but for which the duration of the illness is not specified in the code description (i.e., we do not know the condition has lasted 12 months or longer) also are considered not chronic.