2024 ICD-10-CM Diagnosis Code T50.4X5

Adverse effect of drugs affecting uric acid metabolism

ICD-10-CM Code:
T50.4X5
ICD-10 Code for:
Adverse effect of drugs affecting uric acid metabolism
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances
        (T50)

T50.4X5 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of drugs affecting uric acid metabolism. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Adverse effect of drugs affecting uric acid metabolism

Non-specific codes like T50.4X5 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for adverse effect of drugs affecting uric acid metabolism:

  • Use T50.4X5A for initial encounter - BILLABLE CODE

  • Use T50.4X5D for subsequent encounter - BILLABLE CODE

  • Use T50.4X5S for sequela - BILLABLE CODE

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Allopurinol adverse reaction
  • Allopurinol adverse reaction
  • Allopurinol hypersensitivity syndrome
  • Colchicine adverse reaction
  • Colchicum alkaloid adverse reaction
  • Drug reaction with eosinophilia and systemic symptoms
  • Gout drug side effect
  • Gout monitoring status
  • Probenecid adverse reaction
  • Repeat prescription drug side effect
  • Repeat prescription monitoring status
  • Sulfinpyrazone adverse reaction
  • Uricosuric agent adverse reaction
  • Xanthine oxidase inhibitor adverse reaction
  • Xanthine oxidase inhibitor adverse reaction

Clinical Information

  • Allopurinol

    a xanthine oxidase inhibitor that decreases uric acid production. it also acts as an antimetabolite on some simpler organisms.
  • Benzbromarone

    uricosuric that acts by increasing uric acid clearance. it is used in the treatment of gout.
  • Colchicine

    a major alkaloid from colchicum autumnale l. and found also in other colchicum species. its primary therapeutic use is in the treatment of gout, but it has been used also in the therapy of familial mediterranean fever (periodic disease).
  • Probenecid

    the prototypical uricosuric agent. it inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
  • Sulfinpyrazone

    a uricosuric drug that is used to reduce the serum urate levels in gout therapy. it lacks anti-inflammatory, analgesic, and diuretic properties.
  • Urate Oxidase

    an enzyme that catalyzes the conversion of urate and unidentified products. it is a copper protein. the initial products decompose to form allantoin. ec 1.7.3.3.

Coding Guidelines

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of diuretics and other and unspecified drugs, medicaments and biological substances (T50). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Table of Drugs and Chemicals

The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
(self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AllopurinolT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
AtophanT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
BenemidT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
BenzbromaroneT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
CinchophenT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
ColchicineT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
EtebenecidT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
EthebenecidT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
NeocinchophenT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
OxipurinolT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
PhenoquinT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
ProbenecidT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
Spindle inactivatorT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
SulfinpyrazoneT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
SulphinpyrazoneT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
TisopurineT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
Urate oxidaseT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
Uric acid metabolism drug NECT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6
Uricosuric agentT50.4X1T50.4X2T50.4X3T50.4X4T50.4X5T50.4X6

Patient Education


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as gingko and blood thinners
  • Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.