2024 ICD-10-CM Diagnosis Code T49.5X5

Adverse effect of ophthalmological drugs and preparations

ICD-10-CM Code:
T49.5X5
ICD-10 Code for:
Adverse effect of ophthalmological drugs and preparations
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinorlaryngological and dental drugs
        (T49)

T49.5X5 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of ophthalmological drugs and preparations. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Adverse effect of ophthalmological drugs and preparations

Non-specific codes like T49.5X5 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for adverse effect of ophthalmological drugs and preparations:

  • Use T49.5X5A for initial encounter - BILLABLE CODE

  • Use T49.5X5D for subsequent encounter - BILLABLE CODE

  • Use T49.5X5S for sequela - BILLABLE CODE

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Anticholinesterase parasympathomimetic adverse reaction
  • Anticholinesterase parasympathomimetic adverse reaction
  • Anticholinesterase parasympathomimetic adverse reaction
  • Bilateral glaucoma of eyes caused by drug
  • Bilateral open-angle glaucoma
  • Bulk-forming laxative adverse reaction
  • Bulk-forming laxative adverse reaction
  • Cellulose-derived viscosity modifier adverse reaction
  • Cellulose-derived viscosity modifier adverse reaction
  • Corticosteroid-induced open angle glaucoma
  • Demecarium adverse reaction
  • Dipivefrine adverse reaction
  • Drug-induced glaucoma
  • Drug-induced uveitis
  • Drug-induced uveitis
  • Ecothiopate adverse reaction
  • Glaucoma of left eye caused by drug
  • Glaucoma of right eye caused by drug
  • Hypromellose adverse reaction
  • Hypromellose eye drops adverse reaction
  • Lachesine chloride adverse reaction
  • Levobunolol adverse reaction
  • Metipranolol adverse reaction
  • Metipranolol-induced anterior uveitis
  • Open angle glaucoma of bilateral eyes caused by corticosteroid
  • Open angle glaucoma of left eye caused by corticosteroid
  • Open angle glaucoma of right eye caused by corticosteroid
  • Ophthalmological drug side effect
  • Ophthalmological monitoring status
  • Physostigmine adverse reaction
  • Prednisolone adverse reaction
  • Prednisolone drops adverse reaction
  • Uveitis due to ranibizumab
  • Viscosity modifier adverse reaction
  • Viscosity modifier adverse reaction

Clinical Information

  • Levobunolol

    the l-isomer of bunolol.
  • Metipranolol

    a beta-adrenergic antagonist effective for both beta-1 and beta-2 receptors. it is used as an antiarrhythmic, antihypertensive, and antiglaucoma agent.
  • Physostigmine

    a cholinesterase inhibitor that is rapidly absorbed through membranes. it can be applied topically to the conjunctiva. it also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity.

Coding Guidelines

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinorlaryngological and dental drugs (T49). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Table of Drugs and Chemicals

The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
(self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AmmoniumT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
Ammonium
  »acid tartrate
T49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
Ammonium
  »bromide
T49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
Ammonium
  »carbonate
T49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
Ammonium
  »chloride
T49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
Ammonium
  »chloride
    »expectorant
T49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
Ammonium
  »compounds (household) NEC
T49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
Ammonium
  »compounds (household) NEC
    »fumes (any usage)
T49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
Ammonium
  »compounds (household) NEC
    »industrial
T49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
Ammonium
  »ichthyosulronate
T49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
Ammonium
  »mandelate
T49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
Ammonium
  »sulfamate
T49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
Ammonium
  »sulfonate resin
T49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
BefunololT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
BibrocatholT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
ChloropticT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
Contact lens solutionT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
Cycloplegic drugT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
Demecarium (bromide)T49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
DendridT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
DipivefrineT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
Echothiophate, echothiopate, ecothiopateT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
Ecothiopate iodideT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
EdoxudineT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
EserineT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
EucatropineT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
Eye agents (anti-infective)T49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
Eye drug NECT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
FluorphenylalanineT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
HerplexT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
HydroxyamphetamineT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
HypromelloseT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
LachesineT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
LevobunololT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
Lubricant, eyeT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
Methylparaben (ophthalmic)T49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
MetipranololT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
Miotic drugT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
Mydriatic drugT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
PhospholineT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
PhysostigmineT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
Propylparaben (ophthalmic)T49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
StoxilT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
TetrahydrozolineT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
TetryzolineT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6
VisineT49.5X1T49.5X2T49.5X3T49.5X4T49.5X5T49.5X6

Patient Education


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as gingko and blood thinners
  • Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.