2024 ICD-10-CM Diagnosis Code T45.0X5
Adverse effect of antiallergic and antiemetic drugs
- ICD-10-CM Code:
- T45.0X5
- ICD-10 Code for:
- Adverse effect of antiallergic and antiemetic drugs
- Is Billable?
- Not Valid for Submission
- Code Navigator:
T45.0X5 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of antiallergic and antiemetic drugs. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.
Specific Coding Applicable to Adverse effect of antiallergic and antiemetic drugs
Non-specific codes like T45.0X5 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for adverse effect of antiallergic and antiemetic drugs:
Approximate Synonyms
The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:
- 5-HT3-receptor antagonist adverse reaction
- Acrivastine adverse reaction
- Adverse reaction to antihistamines
- Adverse reaction to mast cell stabilizer
- Adverse reaction to meclizine
- Adverse reaction to xanthine and/or xanthine derivative
- Antazoline adverse reaction
- Antiemetic adverse reaction
- Astemizole adverse reaction
- Azatadine adverse reaction
- Azelastine adverse reaction
- Brompheniramine adverse reaction
- Cetirizine adverse reaction
- Chlorphenamine adverse reaction
- Cinnarizine adverse reaction
- Clemastine adverse reaction
- Cough suppressant adverse reaction
- Cyclizine adverse reaction
- Cyproheptadine adverse reaction
- Dimenhydrinate adverse reaction
- Dimethindene adverse reaction
- Diphenhydramine adverse reaction
- Diphenylpyraline adverse reaction
- Domperidone adverse reaction
- H1 antihistamine adverse reaction
- Ketotifen adverse reaction
- Lodoxamide adverse reaction
- Loratadine adverse reaction
- Mebhydrolin adverse reaction
- Mepyramine adverse reaction
- Metoclopramide adverse reaction
- Oxatomide adverse reaction
- Phenindamine adverse reaction
- Pheniramine adverse reaction
- Terfenadine adverse reaction
- Triprolidine adverse reaction
Clinical Information
Astemizole
antihistamine drug now withdrawn from the market in many countries because of rare but potentially fatal side effects.Brompheniramine
histamine h1 antagonist used in treatment of allergies, rhinitis, and urticaria.Cetirizine
a potent second-generation histamine h1 antagonist that is effective in the treatment of allergic rhinitis, chronic urticaria, and pollen-induced asthma. unlike many traditional antihistamines, it does not cause drowsiness or anticholinergic side effects.Chlorpheniramine
a histamine h1 antagonist used in allergic reactions, hay fever, rhinitis, urticaria, and asthma. it has also been used in veterinary applications. one of the most widely used of the classical antihistaminics, it generally causes less drowsiness and sedation than promethazine.Cinnarizine
a piperazine derivative having histamine h1-receptor and calcium-channel blocking activity with vasodilating and antiemetic properties but it induces parkinsonian disorders.Clemastine
a histamine h1 antagonist used as the hydrogen fumarate in hay fever, rhinitis, allergic skin conditions, and pruritus. it causes drowsiness.Cyclizine
a histamine h1 antagonist given by mouth or parenterally for the control of postoperative and drug-induced vomiting and in motion sickness. (from martindale, the extra pharmacopoeia, 30th ed, p935)Cyproheptadine
a serotonin antagonist and a histamine h1 blocker used as antipruritic, appetite stimulant, antiallergic, and for the post-gastrectomy dumping syndrome, etc.Dimenhydrinate
a drug combination that contains diphenhydramine and theophylline. it is used for treating vertigo, motion sickness, and nausea associated with pregnancy.Dimethindene
a histamine h1 antagonist. it is used in hypersensitivity reactions, in rhinitis, for pruritus, and in some common cold remedies.Diphenhydramine
a histamine h1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. it has some undesired antimuscarinic and sedative effects.Domperidone
a specific blocker of dopamine receptors. it speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.Doxylamine
histamine h1 antagonist with pronounced sedative properties. it is used in allergies and as an antitussive, antiemetic, and hypnotic. doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.Granisetron
a serotonin receptor (5ht-3 selective) antagonist that has been used as an antiemetic for cancer chemotherapy patients.Ketotifen
a cycloheptathiophene blocker of histamine h1 receptors and release of inflammatory mediators. it has been proposed for the treatment of asthma, rhinitis, skin allergies, and anaphylaxis.Methapyrilene
histamine h1 antagonist with sedative action used as a hypnotic and in allergies.Metoclopramide
a dopamine d2 antagonist that is used as an antiemetic.Ondansetron
a competitive serotonin type 3 receptor antagonist. it is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.Pheniramine
one of the histamine h1 antagonists with little sedative action. it is used in treatment of hay fever, rhinitis, allergic dermatoses, and pruritus.Pyrilamine
a histamine h1 antagonist. it has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. it is a common ingredient of cold remedies.Terfenadine
a selective histamine h1-receptor antagonist devoid of central nervous system depressant activity. the drug was used for allergy but withdrawn due to causing long qt syndrome.Tripelennamine
a histamine h1 antagonist with low sedative action but frequent gastrointestinal irritation. it is used to treat asthma; hay fever; urticaria; and rhinitis; and also in veterinary applications. tripelennamine is administered by various routes, including topically.Triprolidine
histamine h1 antagonist used in allergic rhinitis; asthma; and urticaria. it is a component of cough and cold medicines. it may cause drowsiness.
Coding Guidelines
When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.
The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of primarily systemic and hematological agents, not elsewhere classified (T45). Use the following options for the aplicable episode of care:
- A - initial encounter
- D - subsequent encounter
- S - sequela
Table of Drugs and Chemicals
The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.
According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.
Patient Education
Drug Reactions
Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.
What is a drug interaction?
A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:
- Two drugs, such as aspirin and blood thinners
- Drugs and food, such as statins and grapefruit
- Drugs and supplements, such as gingko and blood thinners
- Drugs and medical conditions, such as aspirin and peptic ulcers
Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.
What are side effects?
Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.
What are drug allergies?
Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.
How can I stay safe when taking medicines?
When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.
[Learn More in MedlinePlus]
Code History
- FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
- FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
- FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
- FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
- FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
- FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
- FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
- FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
- FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.