2024 ICD-10-CM Diagnosis Code T44.1X6

Underdosing of other parasympathomimetics [cholinergics]

ICD-10-CM Code:
T44.1X6
ICD-10 Code for:
Underdosing of other parasympathomimetics [cholinergics]
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of drugs primarily affecting the autonomic nervous system
        (T44)

T44.1X6 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of underdosing of other parasympathomimetics [cholinergics]. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Underdosing of other parasympathomimetics [cholinergics]

Non-specific codes like T44.1X6 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for underdosing of other parasympathomimetics [cholinergics]:

  • Use T44.1X6A for initial encounter - BILLABLE CODE

  • Use T44.1X6D for subsequent encounter - BILLABLE CODE

  • Use T44.1X6S for sequela - BILLABLE CODE

Clinical Information

  • Acetylcholine

    a neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.
  • Acetylcholine Release Inhibitors

    compounds that block release of the neurotransmitter acetylcholine.
  • Acetylcholinesterase

    an enzyme that catalyzes the hydrolysis of acetylcholine to choline and acetate. in the cns, this enzyme plays a role in the function of peripheral neuromuscular junctions. ec 3.1.1.7.
  • Cholinergic Agents

    any drug used for its actions on cholinergic systems. included here are agonists and antagonists, drugs that affect the life cycle of acetylcholine, and drugs that affect the survival of cholinergic neurons. the term cholinergic agents is sometimes still used in the narrower sense of muscarinic agonists, although most modern texts discourage that usage.
  • Cholinergic Agonists

    drugs that bind to and activate cholinergic receptors.
  • Cholinergic Antagonists

    drugs that bind to but do not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists.
  • Cholinesterase Inhibitors

    drugs that inhibit cholinesterases. the neurotransmitter acetylcholine is rapidly hydrolyzed, and thereby inactivated, by cholinesterases. when cholinesterases are inhibited, the action of endogenously released acetylcholine at cholinergic synapses is potentiated. cholinesterase inhibitors are widely used clinically for their potentiation of cholinergic inputs to the gastrointestinal tract and urinary bladder, the eye, and skeletal muscles; they are also used for their effects on the heart and the central nervous system.
  • Receptors, Cholinergic

    cell surface proteins that bind acetylcholine with high affinity and trigger intracellular changes influencing the behavior of cells. cholinergic receptors are divided into two major classes, muscarinic and nicotinic, based originally on their affinity for nicotine and muscarine. each group is further subdivided based on pharmacology, location, mode of action, and/or molecular biology.
  • Receptors, Muscarinic

    one of the two major classes of cholinergic receptors. muscarinic receptors were originally defined by their preference for muscarine over nicotine. there are several subtypes (usually m1, m2, m3....) that are characterized by their cellular actions, pharmacology, and molecular biology.
  • Receptors, Nicotinic

    one of the two major classes of cholinergic receptors. nicotinic receptors were originally distinguished by their preference for nicotine over muscarine. they are generally divided into muscle-type and neuronal-type (previously ganglionic) based on pharmacology, and subunit composition of the receptors.
  • Vesicular Acetylcholine Transport Proteins

    vesicular amine transporter proteins that transport the neurotransmitter acetylcholine into small secretory vesicles. proteins of this family contain 12 transmembrane domains and exchange vesicular protons for cytoplasmic acetylcholine.
  • Arecoline

    an alkaloid obtained from the betel nut (areca catechu), fruit of a palm tree. it is an agonist at both muscarinic and nicotinic acetylcholine receptors. it is used in the form of various salts as a ganglionic stimulant, a parasympathomimetic, and a vermifuge, especially in veterinary practice. it has been used as a euphoriant in the pacific islands.
  • Bethanechol

    a slowly hydrolyzing muscarinic agonist with no nicotinic effects. bethanechol is generally used to increase smooth muscle tone, as in the gi tract following abdominal surgery or in urinary retention in the absence of obstruction. it may cause hypotension, heart rate changes, and bronchial spasm.
  • Bethanechol Compounds

    quaternary ammonium compounds that include bethanechol.
  • Carbachol

    a slowly hydrolyzed cholinergic agonist that acts at both muscarinic receptors and nicotinic receptors.
  • Pilocarpine

    a slowly hydrolyzed muscarinic agonist with no nicotinic effects. pilocarpine is used as a miotic and in the treatment of glaucoma.

Coding Guidelines

Underdosing refers to taking less of a medication than is prescribed by a provider or a manufacturer's instruction. Codes for underdosing should never be assigned as principal or first-listed codes. If a patient has a relapse or exacerbation of the medical condition for which the drug is prescribed because of the reduction in dose, then the medical condition itself should be coded.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of drugs primarily affecting the autonomic nervous system (T44). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Table of Drugs and Chemicals

The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
(self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AceclidineT44.1X1T44.1X2T44.1X3T44.1X4T44.1X5T44.1X6
AcetylcholineT44.1X1T44.1X2T44.1X3T44.1X4T44.1X5T44.1X6
Acetylcholine
  »chloride
T44.1X1T44.1X2T44.1X3T44.1X4T44.1X5T44.1X6
Acetylcholine
  »derivative
T44.1X1T44.1X2T44.1X3T44.1X4T44.1X5T44.1X6
ArecolineT44.1X1T44.1X2T44.1X3T44.1X4T44.1X5T44.1X6
Benzpyrinium bromideT44.1X1T44.1X2T44.1X3T44.1X4T44.1X5T44.1X6
BethanecholT44.1X1T44.1X2T44.1X3T44.1X4T44.1X5T44.1X6
Bethanechol
  »chloride
T44.1X1T44.1X2T44.1X3T44.1X4T44.1X5T44.1X6
CarbacholT44.1X1T44.1X2T44.1X3T44.1X4T44.1X5T44.1X6
Carbamylcholine chlorideT44.1X1T44.1X2T44.1X3T44.1X4T44.1X5T44.1X6
Cholinergic (drug) NECT44.1X1T44.1X2T44.1X3T44.1X4T44.1X5T44.1X6
Cholinergic (drug) NEC
  »muscle tone enhancer
T44.1X1T44.1X2T44.1X3T44.1X4T44.1X5T44.1X6
Cholinergic (drug) NEC
  »organophosphorus
T44.1X1T44.1X2T44.1X3T44.1X4T44.1X5T44.1X6
Cholinergic (drug) NEC
  »organophosphorus
    »insecticide
T44.1X1T44.1X2T44.1X3T44.1X4T44.1X5T44.1X6
Cholinergic (drug) NEC
  »organophosphorus
    »nerve gas
T44.1X1T44.1X2T44.1X3T44.1X4T44.1X5T44.1X6
Cholinergic (drug) NEC
  »trimethyl ammonium propanediol
T44.1X1T44.1X2T44.1X3T44.1X4T44.1X5T44.1X6
MethacholineT44.1X1T44.1X2T44.1X3T44.1X4T44.1X5T44.1X6
Parasympathomimetic drug NECT44.1X1T44.1X2T44.1X3T44.1X4T44.1X5T44.1X6
PilocarpineT44.1X1T44.1X2T44.1X3T44.1X4T44.1X5T44.1X6
Pilocarpus (jaborandi) extractT44.1X1T44.1X2T44.1X3T44.1X4T44.1X5T44.1X6

Patient Education


Medication Errors

Medicines treat infectious diseases, prevent problems from chronic diseases, and ease pain. But medicines can also cause harmful reactions if not used correctly. Errors can happen in the hospital, at the health care provider's office, at the pharmacy, or at home. You can help prevent errors by:

  • Knowing your medicines. When you get a prescription, ask the name of the medicine and check to make sure that the pharmacy gave you the right medicine. Make sure that you understand how often you should take the medicine and how long you should take it.
  • Keeping a list of medicines.
    • Write down all of the medicines that you are taking, including the names of your medicines, how much you take, and when you take them. Make sure to include any over-the-counter medicines, vitamins, supplements, and herbs that you take.
    • List the medicines that you are allergic to or that have caused you problems in the past.
    • Take this list with you every time you see a health care provider.
  • Reading medicine labels and following the directions. Don't just rely on your memory - read the medication label every time. Be especially careful when giving medicines to children.
  • Asking questions. If you don't know the answers to these questions, ask your health care provider or pharmacist:
    • Why am I taking this medicine?
    • What are the common side effects?
    • What should I do if I have side effects?
    • When should I stop this medicine?
    • Can I take this medicine with the other medicines and supplements on my list?
    • Do I need to avoid certain foods or alcohol while taking this medicine?

Food and Drug Administration


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.