2024 ICD-10-CM Diagnosis Code T43.5

Poisoning by, adverse effect of and underdosing of other and unspecified antipsychotics and neuroleptics

ICD-10-CM Code:
T43.5
ICD-10 Code for:
And unsp antipsychotics and neuroleptics
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified
        (T43)

T43.5 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of poisoning by, adverse effect of and underdosing of other and unspecified antipsychotics and neuroleptics. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Unspecified diagnosis codes like T43.5 are acceptable when clinical information is unknown or not available about a particular condition. Although a more specific code is preferable, unspecified codes should be used when such codes most accurately reflect what is known about a patient's condition. Specific diagnosis codes should not be used if not supported by the patient's medical record.

Specific Coding Applicable to And unsp antipsychotics and neuroleptics

Non-specific codes like T43.5 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for and unsp antipsychotics and neuroleptics:

  • T43.50 for Poisoning by, adverse effect of and underdosing of unspecified antipsychotics and neuroleptics - NON-BILLABLE CODE

  • T43.501 for Poisoning by unspecified antipsychotics and neuroleptics, accidental (unintentional) - NON-BILLABLE CODE

  • Use T43.501A for initial encounter - BILLABLE CODE

  • Use T43.501D for subsequent encounter - BILLABLE CODE

  • Use T43.501S for sequela - BILLABLE CODE

  • T43.502 for Poisoning by unspecified antipsychotics and neuroleptics, intentional self-harm - NON-BILLABLE CODE

  • Use T43.502A for initial encounter - BILLABLE CODE

  • Use T43.502D for subsequent encounter - BILLABLE CODE

  • Use T43.502S for sequela - BILLABLE CODE

  • T43.503 for Poisoning by unspecified antipsychotics and neuroleptics, assault - NON-BILLABLE CODE

  • Use T43.503A for initial encounter - BILLABLE CODE

  • Use T43.503D for subsequent encounter - BILLABLE CODE

  • Use T43.503S for sequela - BILLABLE CODE

  • T43.504 for Poisoning by unspecified antipsychotics and neuroleptics, undetermined - NON-BILLABLE CODE

  • Use T43.504A for initial encounter - BILLABLE CODE

  • Use T43.504D for subsequent encounter - BILLABLE CODE

  • Use T43.504S for sequela - BILLABLE CODE

  • T43.505 for Adverse effect of unspecified antipsychotics and neuroleptics - NON-BILLABLE CODE

  • Use T43.505A for initial encounter - BILLABLE CODE

  • Use T43.505D for subsequent encounter - BILLABLE CODE

  • Use T43.505S for sequela - BILLABLE CODE

  • T43.506 for Underdosing of unspecified antipsychotics and neuroleptics - NON-BILLABLE CODE

  • Use T43.506A for initial encounter - BILLABLE CODE

  • Use T43.506D for subsequent encounter - BILLABLE CODE

  • Use T43.506S for sequela - BILLABLE CODE

  • T43.59 for Poisoning by, adverse effect of and underdosing of other antipsychotics and neuroleptics - NON-BILLABLE CODE

  • T43.591 for Poisoning by other antipsychotics and neuroleptics, accidental (unintentional) - NON-BILLABLE CODE

  • Use T43.591A for initial encounter - BILLABLE CODE

  • Use T43.591D for subsequent encounter - BILLABLE CODE

  • Use T43.591S for sequela - BILLABLE CODE

  • T43.592 for Poisoning by other antipsychotics and neuroleptics, intentional self-harm - NON-BILLABLE CODE

  • Use T43.592A for initial encounter - BILLABLE CODE

  • Use T43.592D for subsequent encounter - BILLABLE CODE

  • Use T43.592S for sequela - BILLABLE CODE

  • T43.593 for Poisoning by other antipsychotics and neuroleptics, assault - NON-BILLABLE CODE

  • Use T43.593A for initial encounter - BILLABLE CODE

  • Use T43.593D for subsequent encounter - BILLABLE CODE

  • Use T43.593S for sequela - BILLABLE CODE

  • T43.594 for Poisoning by other antipsychotics and neuroleptics, undetermined - NON-BILLABLE CODE

  • Use T43.594A for initial encounter - BILLABLE CODE

  • Use T43.594D for subsequent encounter - BILLABLE CODE

  • Use T43.594S for sequela - BILLABLE CODE

  • T43.595 for Adverse effect of other antipsychotics and neuroleptics - NON-BILLABLE CODE

  • Use T43.595A for initial encounter - BILLABLE CODE

  • Use T43.595D for subsequent encounter - BILLABLE CODE

  • Use T43.595S for sequela - BILLABLE CODE

  • T43.596 for Underdosing of other antipsychotics and neuroleptics - NON-BILLABLE CODE

  • Use T43.596A for initial encounter - BILLABLE CODE

  • Use T43.596D for subsequent encounter - BILLABLE CODE

  • Use T43.596S for sequela - BILLABLE CODE

Coding Guidelines

When coding a poisoning or reaction to the improper use of a medication (e.g., overdose, wrong substance given or taken in error, wrong route of administration), first assign the appropriate code from categories T36-T50. The poisoning codes have an associated intent as their 5th or 6th character (accidental, intentional self-harm, assault and undetermined. If the intent of the poisoning is unknown or unspecified, code the intent as accidental intent. The undetermined intent is only for use if the documentation in the record specifies that the intent cannot be determined. Use additional code(s) for all manifestations of poisonings.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of psychotropic drugs, not elsewhere classified (T43). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.


Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • poisoning by, adverse effect of and underdosing of rauwolfia T46.5

Patient Education


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as gingko and blood thinners
  • Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.