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  6. 2024 ICD-10-CM Code T39.315

2024 ICD-10-CM Diagnosis Code T39.315

Adverse effect of propionic acid derivatives

ICD-10-CM Code:
T39.315
ICD-10 Code for:
Adverse effect of propionic acid derivatives
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of nonopioid analgesics, antipyretics and antirheumatics
        (T39)

T39.315 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of propionic acid derivatives. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Adverse effect of propionic acid derivatives

Non-specific codes like T39.315 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for adverse effect of propionic acid derivatives:

  • Use T39.315A for initial encounter - BILLABLE CODE

  • Use T39.315D for subsequent encounter - BILLABLE CODE

  • Use T39.315S for sequela - BILLABLE CODE

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Adverse reaction to ibuprofen
  • Adverse reaction to ketoprofen
  • Adverse reaction to naproxen
  • Fenoprofen adverse reaction
  • Flurbiprofen adverse reaction
  • Propionic acid derivative adverse reaction
  • Tiaprofenic acid adverse reaction

Clinical Information

  • Fenoprofen

    a propionic acid derivative that is used as a non-steroidal anti-inflammatory agent.

  • Flurbiprofen

    an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. it has been shown to reduce bone resorption in periodontal disease by inhibiting carbonic anhydrase.

  • Ibuprofen

    a non-steroidal anti-inflammatory agent with analgesic, antipyretic, and anti-inflammatory properties

  • Ketoprofen

    an ibuprofen-type anti-inflammatory analgesic and antipyretic. it is used in the treatment of rheumatoid arthritis and osteoarthritis.

  • Carboxylesterase

    carboxylesterase is a serine-dependent esterase with wide substrate specificity. the enzyme is involved in the detoxification of xenobiotics and the activation of ester and of amide prodrugs.

  • Naproxen

    an anti-inflammatory agent with analgesic and antipyretic properties. both the acid and its sodium salt are used in the treatment of rheumatoid arthritis and other rheumatic or musculoskeletal disorders, dysmenorrhea, and acute gout.

  • Oxaprozin

    an oxazole-propionic acid derivative, cyclooxygenase inhibitor, and non-steroidal anti-inflammatory drug that is used in the treatment of pain and inflammation associated with of osteoarthritis; rheumatoid arthritis; and arthritis, juvenile.

  • Suprofen

    an ibuprofen-type anti-inflammatory analgesic and antipyretic. it inhibits prostaglandin synthesis and has been proposed as an anti-arthritic.

Coding Guidelines

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of nonopioid analgesics, antipyretics and antirheumatics (T39). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Table of Drugs and Chemicals

The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)		 Poisoning
Accidental
(self-harm)		 Poisoning
Assault		 Poisoning
Undetermined		 Adverse
effect		 Underdosing
CarprofenT39.311T39.312T39.313T39.314T39.315T39.316
EsflurbiprofenT39.311T39.312T39.313T39.314T39.315T39.316
FenoprofenT39.311T39.312T39.313T39.314T39.315T39.316
FlurbiprofenT39.311T39.312T39.313T39.314T39.315T39.316
IbufenacT39.311T39.312T39.313T39.314T39.315T39.316
IbuprofenT39.311T39.312T39.313T39.314T39.315T39.316
IbuproxamT39.311T39.312T39.313T39.314T39.315T39.316
KetoprofenT39.311T39.312T39.313T39.314T39.315T39.316
NaproxenT39.311T39.312T39.313T39.314T39.315T39.316
OxaprozinT39.311T39.312T39.313T39.314T39.315T39.316
SuprofenT39.311T39.312T39.313T39.314T39.315T39.316
Tiaprofenic acidT39.311T39.312T39.313T39.314T39.315T39.316

Patient Education


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as gingko and blood thinners
  • Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.