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  6. 2024 ICD-10-CM Code T39.1X5

2024 ICD-10-CM Diagnosis Code T39.1X5

Adverse effect of 4-Aminophenol derivatives

ICD-10-CM Code:
T39.1X5
ICD-10 Code for:
Adverse effect of 4-Aminophenol derivatives
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of nonopioid analgesics, antipyretics and antirheumatics
        (T39)

T39.1X5 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of 4-aminophenol derivatives. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Adverse effect of 4-Aminophenol derivatives

Non-specific codes like T39.1X5 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for adverse effect of 4-aminophenol derivatives:

  • Use T39.1X5A for initial encounter - BILLABLE CODE

  • Use T39.1X5D for subsequent encounter - BILLABLE CODE

  • Use T39.1X5S for sequela - BILLABLE CODE

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Adverse reaction caused by acetaminophen
  • Adverse reaction to acetanilide
  • Adverse reaction to phenacetin
  • Para-aminophenol derivative adverse reaction

Clinical Information

  • Acetaminophen

    analgesic antipyretic derivative of acetanilide. it has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.

  • Arylsulfotransferase

    a sulfotransferase that catalyzes the sulfation of a phenol in the presence of 3'-phosphoadenylylsulfate as sulfate donor to yield an aryl sulfate and adenosine 3',5'-bisphosphate. a number of aromatic compounds can act as acceptors; however, organic hydroxylamines are not substrates. sulfate conjugation by this enzyme is a major pathway for the biotransformation of phenolic and catechol drugs as well as neurotransmitters. ec 2.8.2.1.

  • Cytochrome P-450 CYP1A2

    a cytochrome p450 enzyme subtype that has specificity for relatively planar heteroaromatic small molecules, such as caffeine and acetaminophen.

  • Phenacetin

    a phenylacetamide that was formerly used in analgesics but nephropathy and methemoglobinemia led to its withdrawal from the market. (from smith and reynard, textbook of pharmacology,1991, p431)

Coding Guidelines

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of nonopioid analgesics, antipyretics and antirheumatics (T39). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Table of Drugs and Chemicals

The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)		 Poisoning
Accidental
(self-harm)		 Poisoning
Assault		 Poisoning
Undetermined		 Adverse
effect		 Underdosing
P-AcetamidophenolT39.1X1T39.1X2T39.1X3T39.1X4T39.1X5T39.1X6
AcetaminophenT39.1X1T39.1X2T39.1X3T39.1X4T39.1X5T39.1X6
AcetaminosalolT39.1X1T39.1X2T39.1X3T39.1X4T39.1X5T39.1X6
AcetanilideT39.1X1T39.1X2T39.1X3T39.1X4T39.1X5T39.1X6
AcetophenetedinT39.1X1T39.1X2T39.1X3T39.1X4T39.1X5T39.1X6
4-Aminophenol derivativesT39.1X1T39.1X2T39.1X3T39.1X4T39.1X5T39.1X6
Bromo-seltzerT39.1X1T39.1X2T39.1X3T39.1X4T39.1X5T39.1X6
ExalginT39.1X1T39.1X2T39.1X3T39.1X4T39.1X5T39.1X6
PanadolT39.1X1T39.1X2T39.1X3T39.1X4T39.1X5T39.1X6
Para-acetamidophenolT39.1X1T39.1X2T39.1X3T39.1X4T39.1X5T39.1X6
Para-aminophenol derivativesT39.1X1T39.1X2T39.1X3T39.1X4T39.1X5T39.1X6
ParacetamolT39.1X1T39.1X2T39.1X3T39.1X4T39.1X5T39.1X6
PhenacetinT39.1X1T39.1X2T39.1X3T39.1X4T39.1X5T39.1X6

Patient Education


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as gingko and blood thinners
  • Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.