2024 ICD-10-CM Diagnosis Code T37.0X5

Adverse effect of sulfonamides

ICD-10-CM Code:
T37.0X5
ICD-10 Code for:
Adverse effect of sulfonamides
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Injury, poisoning and certain other consequences of external causes
    (S00–T88)
    • Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances
      (T36-T50)
      • Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics
        (T37)

T37.0X5 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of adverse effect of sulfonamides. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Adverse effect of sulfonamides

Non-specific codes like T37.0X5 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for adverse effect of sulfonamides:

  • Use T37.0X5A for initial encounter - BILLABLE CODE

  • Use T37.0X5D for subsequent encounter - BILLABLE CODE

  • Use T37.0X5S for sequela - BILLABLE CODE

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Adverse reaction to salicylate
  • Adverse reaction to sulfamethoxazole
  • Adverse reaction to sulfamethoxazole and/or trimethoprim
  • Allergic reaction caused by sulfonamide
  • Calcium sulfaloxate adverse reaction
  • Phthalylsulfathiazole adverse reaction
  • Sulfadiazine adverse reaction
  • Sulfadimethoxine adverse reaction
  • Sulfadimidine adverse reaction
  • Sulfafurazole adverse reaction
  • Sulfaguanidine adverse reaction
  • Sulfametopyrazine adverse reaction
  • Sulfasalazine adverse reaction
  • Sulfaurea adverse reaction
  • Sulfonamide adverse reaction
  • Sulfonamide antibiotic adverse reaction
  • Sulfonamide diuretic adverse reaction

Clinical Information

  • Acedapsone

    acetylated sulfone that is slowly metabolized to give long-term, low blood levels of dapsone. it has antimicrobial and antimalarial action, but is mainly used as a depot leprostatic agent.
  • Sulfachlorpyridazine

    a sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.
  • Silver Sulfadiazine

    antibacterial used topically in burn therapy.
  • Sulfadiazine

    one of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections.
  • Sulfadimethoxine

    a sulfanilamide that is used as an anti-infective agent.
  • Sulfadoxine

    a long acting sulfonamide that is used, usually in combination with other drugs, for respiratory, urinary tract, and malarial infections.
  • Sulfaguanidine

    a sulfanilamide antimicrobial agent that is used to treat enteric infections.
  • Sulfalene

    long-acting plasma-bound sulfonamide used for respiratory and urinary tract infections and also for malaria.
  • Sulfamerazine

    a sulfanilamide that is used as an antibacterial agent.
  • Sulfameter

    long acting sulfonamide used in leprosy, urinary, and respiratory tract infections.
  • Sulfamethazine

    a sulfanilamide anti-infective agent. it has a spectrum of antimicrobial action similar to other sulfonamides.
  • Sulfamethizole

    a sulfathiazole antibacterial agent.
  • Sulfamethoxazole

    a bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. its broad spectrum of activity has been limited by the development of resistance. (from martindale, the extra pharmacopoeia, 30th ed, p208)
  • Trimethoprim, Sulfamethoxazole Drug Combination

    a drug combination with broad-spectrum antibacterial activity against both gram-positive and gram-negative organisms. it is effective in the treatment of many infections, including pneumocystis pneumonia in aids.
  • Sulfamethoxypyridazine

    a sulfanilamide antibacterial agent.
  • Sulfamonomethoxine

    long acting sulfonamide antibacterial agent.
  • Sulfamoxole

    a sulfanilamide antibacterial agent.
  • Sulfanilamide

    a short-acting sulfonamide used as an anti-infective agent. it has lower anti-bacterial activity than sulfamethoxazole.
  • Sulfanilamides

    compounds based on 4-aminobenzenesulfonamide. the '-anil-' part of the name refers to aniline.
  • Sulfaphenazole

    a sulfonilamide anti-infective agent.
  • Sulfapyridine

    antibacterial, potentially toxic, used to treat certain skin diseases.
  • Sulfasalazine

    a drug that is used in the management of inflammatory bowel diseases. its activity is generally considered to lie in its metabolic breakdown product, 5-aminosalicylic acid (see mesalamine) released in the colon. (from martindale, the extra pharmacopoeia, 30th ed, p907)
  • Sulfathiazole

    a sulfathiazole compound that is used as a short-acting anti-infective agent. it is no longer commonly used systemically due to its toxicity, but may still be applied topically in combination with other drugs for the treatment of vaginal and skin infections, and is still used in veterinary medicine.
  • Sulfathiazoles

    sulfanilamides consisting of a 4-aminobenzenesulfonamido group at the 2-position of 1,3-thiazole. they are often used as anti-infective agents.
  • Sulfisomidine

    a sulfanilamide antibacterial agent.
  • Sulfisoxazole

    a short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms.

Coding Guidelines

When coding an adverse effect of a drug that has been correctly prescribed and properly administered, assign the appropriate code for the nature of the adverse effect followed by the appropriate code for the adverse effect of the drug.

The appropriate 7th character is to be added to each code from block Poisoning by, adverse effect of and underdosing of other systemic anti-infectives and antiparasitics (T37). Use the following options for the aplicable episode of care:

  • A - initial encounter
  • D - subsequent encounter
  • S - sequela

Table of Drugs and Chemicals

The code is referenced in the Table of Drugs and Chemicals, this table contains a classification of drugs, industrial solvents, corrosive gases, noxious plants, pesticides, and other toxic agents.

According to ICD-10-CM coding guidelines it is advised to do not code directly from the Table of Drugs and Chemicals, instead always refer back to the Tabular List when doing the initial coding. Each substance in the table is assigned a code according to the poisoning classification and external causes of adverse effects. It is important to use as many codes as necessary to specify all reported drugs, medicinal or chemical substances. If the same diagnosis code describes the causative agent for more than one adverse reaction, poisoning, toxic effect or underdosing, utilize the code only once.

Substance Poisoning
Accidental
(unintentional)
Poisoning
Accidental
(self-harm)
Poisoning
Assault
Poisoning
Undetermined
Adverse
effect
Underdosing
AcedapsoneT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
AcesulfamethoxypyridazineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
AcetylsulfamethoxypyridazineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
AzosulfamideT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
AzulfidineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
DiaphenylsulfoneT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
DisulfanilamideT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
NeoprontosilT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
PhthalylsulfathiazoleT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
ProntosilT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SalazosulfapyridineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SalicylazosulfapyridineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SuccinylsulfathiazoleT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfachlorpyridazineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfacitineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
Sulfadiasulfone sodiumT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfadiazineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
Sulfadiazine
  »silver (topical)
T37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfadimethoxineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfadimidineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfadoxineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
Sulfadoxine
  »with pyrimethamine
T37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfaethidoleT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfafurazoleT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfaguanidineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfaleneT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfaloxateT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
Sulfaloxic acidT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfamerazineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfameterT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfamethazineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfamethizoleT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfamethoxazoleT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
Sulfamethoxazole
  »with trimethoprim
T37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfamethoxydiazineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfamethoxypyridazineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfamethylthiazoleT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfametoxydiazineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfamonomethoxineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfamoxoleT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfanilamideT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfanilylguanidineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfaperinT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfaphenazoleT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfaphenylthiazoleT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfaproxylineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfapyridineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfapyrimidineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfasalazineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfasuxidineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfasymazineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfathiazoleT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfisomidineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulfisoxazoleT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
Sulfisoxazole
  »ophthalmic preparation
T37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
Sulfonamide NECT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
Sulfonamide NEC
  »eye
T37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulphadiazineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulphadimethoxineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulphadimidineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulphafurazoleT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulphamethizoleT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulphamethoxazoleT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulphaphenazoleT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulphapyridineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
SulphasalazineT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6
TrisulfapyrimidinesT37.0X1T37.0X2T37.0X3T37.0X4T37.0X5T37.0X6

Patient Education


Drug Reactions

Most of the time, medicines make our lives better. They reduce aches and pains, fight infections, and control problems such as high blood pressure or diabetes. But medicines can also cause unwanted reactions, such as drug interactions, side effects, and allergies.

What is a drug interaction?

A drug interaction is a change in the way a drug acts in the body when taken with certain other drugs, foods, or supplements or when taken while you have certain medical conditions. Examples include:

  • Two drugs, such as aspirin and blood thinners
  • Drugs and food, such as statins and grapefruit
  • Drugs and supplements, such as gingko and blood thinners
  • Drugs and medical conditions, such as aspirin and peptic ulcers

Interactions could cause a drug to be more or less effective, cause side effects, or change the way one or both drugs work.

What are side effects?

Side effects are unwanted, usually unpleasant, effects caused by medicines. Most are mild, such as a stomachache, dry mouth, or drowsiness, and go away after you stop taking the medicine. Others can be more serious. Sometimes a drug can interact with a disease that you have and cause a side effect. For example, if you have a heart condition, certain decongestants can cause you to have a rapid heartbeat.

What are drug allergies?

Drug allergies are another type of reaction. They can range from mild to life-threatening. Skin reactions, such as hives and rashes, are the most common type. Anaphylaxis, a serious allergic reaction, is less common.

How can I stay safe when taking medicines?

When you start a new prescription or over-the-counter medicine, make sure you understand how to take it correctly. Know which other medicines, foods, and supplements you need to avoid. Always talk to your health care provider or pharmacist if you have questions about your medicines.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.