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  6. 2024 ICD-10-CM Code H33.10

2024 ICD-10-CM Diagnosis Code H33.10

Unspecified retinoschisis

ICD-10-CM Code:
H33.10
ICD-10 Code for:
Unspecified retinoschisis
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Diseases of the eye and adnexa
    (H00–H59)
    • Disorders of choroid and retina
      (H30-H36)
      • Retinal detachments and breaks
        (H33)

H33.10 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of unspecified retinoschisis. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Unspecified diagnosis codes like H33.10 are acceptable when clinical information is unknown or not available about a particular condition. Although a more specific code is preferable, unspecified codes should be used when such codes most accurately reflect what is known about a patient's condition. Specific diagnosis codes should not be used if not supported by the patient's medical record.

Specific Coding Applicable to Unspecified retinoschisis

Non-specific codes like H33.10 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for unspecified retinoschisis:

  • Use H33.101 for Unspecified retinoschisis, right eye - BILLABLE CODE

  • Use H33.102 for Unspecified retinoschisis, left eye - BILLABLE CODE

  • Use H33.103 for Unspecified retinoschisis, bilateral - BILLABLE CODE

  • Use H33.109 for Unspecified retinoschisis, unspecified eye - BILLABLE CODE

Clinical Information

  • Retinoschisis

    a vitreoretinal dystrophy characterized by splitting of the neuroretinal layers. it occurs in two forms: degenerative retinoschisis and x chromosome-linked juvenile retinoschisis.

  • Juvenile X-Linked Retinoschisis

    a genetic disorder affecting primarily males. it is caused by mutations of the xlrs1 gene mapped to chromosome xp22. it affects the cells of the retina, resulting in retinal degeneration and poor eyesight.

  • Retinoschisin Protein|X-Linked Juvenile Retinoschisis Protein

    retinoschisin protein (224 aa, 26 kda) is a development protein that is encoded by the human rs1 gene and is involved in retinal development and aging, and may play a role in cell-cell adhesion.

  • Retinoschisis

    an inherited or acquired disorder characterized by splitting of the retina into two layers. it results in loss of vision.

  • RS1 Gene|RS1|RS1|Retinoschisis (X-Linked, Juvenile) 1 Gene

    this gene is involved in development, aging, and cell-cell adhesion in the retina.

  • RS1 wt Allele|Retinoschisis (X-Linked, Juvenile) 1 wt Allele

    human rs1 wild-type allele is located within xp22.2-p22.1 and is approximately 32 kb in length. this allele, which encodes retinoschisin protein, plays roles in retinal development and aging, and may have a role in cell-cell adhesion. mutations in this gene are associated with x-linked juvenile retinoschisis.

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Patient Education


Retinal Disorders

The retina is a layer of tissue in the back of your eye that senses light and sends images to your brain. In the center of this nerve tissue is the macula. It provides the sharp, central vision needed for reading, driving and seeing fine detail.

Retinal disorders affect this vital tissue. They can affect your vision, and some can be serious enough to cause blindness. Examples are:

  • Macular degeneration - a disease that destroys your sharp, central vision
  • Diabetic eye disease
  • Retinal detachment - a medical emergency, when the retina is pulled away from the back of the eye
  • Retinoblastoma - cancer of the retina. It is most common in young children.
  • Macular pucker - scar tissue on the macula
  • Macular hole - a small break in the macula that usually happens to people over 60
  • Floaters - cobwebs or specks in your field of vision

NIH: National Eye Institute


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.