2024 ICD-10-CM Diagnosis Code G12.29

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

• Anterior horn cell disease
• Anterior horn cell disease
• Bulbar weakness
• Lethal arthrogryposis with anterior horn cell disease
• Madras-type motor neurone disease
• Paraneoplastic motor neurone disease
• Progressive pseudobulbar palsy
• Pseudobulbar palsy
• Supranuclear paralysis
• Troyer syndrome
• Upper motor neuron disease
• Western Pacific motor neurone disease

Clinical Information

• Amyotrophic Lateral Sclerosis

  a degenerative disorder affecting upper motor neurons in the brain and lower motor neurons in the brain stem and spinal cord. disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. clinical manifestations include progressive weakness, atrophy, fasciculation, hyperreflexia, dysarthria, dysphagia, and eventual paralysis of respiratory function. pathologic features include the replacement of motor neurons with fibrous astrocytes and atrophy of anterior spinal nerve roots and corticospinal tracts. (from adams et al., principles of neurology, 6th ed, pp1089-94)

• Motor Neuron Disease

  diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. clinical subtypes are distinguished by the major site of degeneration. in amyotrophic lateral sclerosis there is involvement of upper, lower, and brainstem motor neurons. in progressive muscular atrophy and related syndromes (see muscular atrophy, spinal) the motor neurons in the spinal cord are primarily affected. with progressive bulbar palsy (bulbar palsy, progressive), the initial degeneration occurs in the brainstem. in primary lateral sclerosis, the cortical neurons are affected in isolation. (adams et al., principles of neurology, 6th ed, p1089)

• Pseudobulbar Palsy

  a syndrome characterized by dysarthria, dysphagia, dysphonia, impairment of voluntary movements of tongue and facial muscles, and emotional lability. this condition is caused by diseases that affect the motor fibers that travel from the cerebral cortex to the lower brain stem (i.e., corticobulbar tracts); including multiple sclerosis; motor neuron disease; and cerebrovascular disorders. (from adams et al., principles of neurology, 6th ed, p489)

• Pseudobulbar Palsy

  a condition affecting cranial nerves ix-xii resulting from upper motor neuron damage arising from a variety of causes.

Convert G12.29 to ICD-9-CM

• ICD-9-CM Code: 335.29 - Motor neuron disease NEC
  Approximate Flag - The approximate mapping means there is not an exact match between the ICD-10 and ICD-9 codes and the mapped code is not a precise representation of the original code.

Patient Education

Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a nervous system disease that attacks nerve cells called neurons in your brain and spinal cord. These neurons transmit messages from your brain and spinal cord to your voluntary muscles - the ones you can control, like in your arms and legs. At first, this causes mild muscle problems. Some people notice:

• Trouble walking or running
• Trouble writing
• Speech problems

Eventually, you lose your strength and cannot move. When muscles in your chest fail, you cannot breathe. A breathing machine can help, but most people with ALS die from respiratory failure.

The disease usually strikes between age 40 and 60. More men than women get it. No one knows what causes ALS. It can run in families, but usually it strikes at random. There is no cure. Medicines can relieve symptoms and, sometimes, prolong survival.

NIH: National Institute of Neurological Disorders and Stroke

[Learn More in MedlinePlus]

Neuromuscular Disorders

Neuromuscular disorders affect your neuromuscular system. They can cause problems with:

• The nerves that control your muscles
• Your muscles
• Communication between your nerves and muscles

These disorders can cause your muscles to become weak and waste away. You may also have symptoms such as spasms, twitching, and pain.

Examples of neuromuscular disorders include:

• Amyotrophic lateral sclerosis
• Muscular dystrophy
• Myasthenia gravis
• Spinal muscular atrophy

There can be different causes for these diseases. Many of them are genetic.This means they are inherited (run in families) or are caused by a new mutation in your genes. Some neuromuscular disorders are autoimmune diseases. Sometimes the cause is unknown.

Many neuromuscular diseases have no cure. But treatments may improve symptoms, increase mobility, and lengthen life.

[Learn More in MedlinePlus]

Code History

• FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
• FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
• FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
• FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
• FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
• FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
• FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
• FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
• FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.