Version 2024

2024 ICD-10-CM Diagnosis Code E71.5

Peroxisomal disorders

ICD-10-CM Code:
E71.5
ICD-10 Code for:
Peroxisomal disorders
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Endocrine, nutritional and metabolic diseases
    (E00–E89)
    • Metabolic disorders
      (E70-E88)
      • Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
        (E71)

E71.5 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of peroxisomal disorders. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Peroxisomal disorders

Non-specific codes like E71.5 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for peroxisomal disorders:

  • Use E71.50 for Peroxisomal disorder, unspecified - BILLABLE CODE

  • E71.51 for Disorders of peroxisome biogenesis - NON-BILLABLE CODE

  • Use E71.510 for Zellweger syndrome - BILLABLE CODE

  • Use E71.511 for Neonatal adrenoleukodystrophy - BILLABLE CODE

  • Use E71.518 for Other disorders of peroxisome biogenesis - BILLABLE CODE

  • E71.52 for X-linked adrenoleukodystrophy - NON-BILLABLE CODE

  • Use E71.520 for Childhood cerebral X-linked adrenoleukodystrophy - BILLABLE CODE

  • Use E71.521 for Adolescent X-linked adrenoleukodystrophy - BILLABLE CODE

  • Use E71.522 for Adrenomyeloneuropathy - BILLABLE CODE

  • Use E71.528 for Other X-linked adrenoleukodystrophy - BILLABLE CODE

  • Use E71.529 for X-linked adrenoleukodystrophy, unspecified type - BILLABLE CODE

  • Use E71.53 for Other group 2 peroxisomal disorders - BILLABLE CODE

  • E71.54 for Other peroxisomal disorders - NON-BILLABLE CODE

  • Use E71.540 for Rhizomelic chondrodysplasia punctata - BILLABLE CODE

  • Use E71.541 for Zellweger-like syndrome - BILLABLE CODE

  • Use E71.542 for Other group 3 peroxisomal disorders - BILLABLE CODE

  • Use E71.548 for Other peroxisomal disorders - BILLABLE CODE

Clinical Information

  • Peroxisomal Disorders

    a heterogeneous group of inherited metabolic disorders marked by absent or dysfunctional peroxisomes. peroxisomal enzymatic abnormalities may be single or multiple. biosynthetic peroxisomal pathways are compromised, including the ability to synthesize ether lipids and to oxidize long-chain fatty acid precursors. diseases in this category include zellweger syndrome; infantile refsum disease; rhizomelic chondrodysplasia (chondrodysplasia punctata, rhizomelic); hyperpipecolic acidemia; neonatal adrenoleukodystrophy; and adrenoleukodystrophy (x-linked). neurologic dysfunction is a prominent feature of most peroxisomal disorders.

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.


Type 1 Excludes

Type 1 Excludes
A type 1 excludes note is a pure excludes note. It means "NOT CODED HERE!" An Excludes1 note indicates that the code excluded should never be used at the same time as the code above the Excludes1 note. An Excludes1 is used when two conditions cannot occur together, such as a congenital form versus an acquired form of the same condition.
  • Schilder's disease G37.0

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Patient Education


Metabolic Disorders

Metabolism is the process your body uses to get or make energy from the food you eat. Food is made up of proteins, carbohydrates, and fats. Chemicals in your digestive system break the food parts down into sugars and acids, your body's fuel. Your body can use this fuel right away, or it can store the energy in your body tissues, such as your liver, muscles, and body fat.

A metabolic disorder occurs when abnormal chemical reactions in your body disrupt this process. When this happens, you might have too much of some substances or too little of other ones that you need to stay healthy. There are different groups of disorders. Some affect the breakdown of amino acids, carbohydrates, or lipids. Another group, mitochondrial diseases, affects the parts of the cells that produce the energy.

You can develop a metabolic disorder when some organs, such as your liver or pancreas, become diseased or do not function normally. Diabetes is an example.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.