Version 2024

2024 ICD-10-CM Diagnosis Code E27

Other disorders of adrenal gland

ICD-10-CM Code:
E27
ICD-10 Code for:
Other disorders of adrenal gland
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Endocrine, nutritional and metabolic diseases
    (E00–E89)
    • Disorders of other endocrine glands
      (E20-E35)
      • Other disorders of adrenal gland
        (E27)

E27 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of other disorders of adrenal gland. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Other disorders of adrenal gland

Non-specific codes like E27 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for other disorders of adrenal gland:

  • Use E27.0 for Other adrenocortical overactivity - BILLABLE CODE

  • Use E27.1 for Primary adrenocortical insufficiency - BILLABLE CODE

  • Use E27.2 for Addisonian crisis - BILLABLE CODE

  • Use E27.3 for Drug-induced adrenocortical insufficiency - BILLABLE CODE

  • E27.4 for Other and unspecified adrenocortical insufficiency - NON-BILLABLE CODE

  • Use E27.40 for Unspecified adrenocortical insufficiency - BILLABLE CODE

  • Use E27.49 for Other adrenocortical insufficiency - BILLABLE CODE

  • Use E27.5 for Adrenomedullary hyperfunction - BILLABLE CODE

  • Use E27.8 for Other specified disorders of adrenal gland - BILLABLE CODE

  • Use E27.9 for Disorder of adrenal gland, unspecified - BILLABLE CODE

Patient Education


Adrenal Gland Disorders

What are adrenal glands?

Your adrenal glands are two small organs that sit on top of each kidney. The adrenal glands make different types of hormones you need to stay alive and healthy. Hormones are chemicals that travel in your bloodstream and control how different parts of your body work.

The adrenal glands make the hormones cortisol, aldosterone, adrenaline, and noradrenaline. They also make hormones that your body uses to make sex hormones (estrogen and testosterone). All of these hormones do many important jobs, including:

  • Turning food into energy and managing blood sugar levels
  • Balancing salt and water
  • Keeping blood pressure normal
  • Responding to illness and stress (your "fight or flight" response)
  • Timing when and how fast a child develops sexually
  • Supporting pregnancy

What are adrenal gland disorders?

When you have an adrenal gland disorder, your body makes too much or too little of one or more hormones. The symptoms depend on the type of problem you have and how much it affects the hormone levels in your body.

There are many types of adrenal gland disorders, including:

  • Addison's Disease - a condition in which the adrenal glands don't make enough cortisol
  • Cushing's Syndrome - a condition caused by too much cortisol in the body, often from taking steroid medicines for a long time
  • Aldosterone-producing adenoma - a benign tumor (not cancer) that makes too much aldosterone and may cause serious high blood pressure
  • Hereditary paraganglioma-pheochromocytoma - an inherited condition causing different types of tumors that make adrenaline and other hormones. Some tumors may become cancerous.
  • Adrenal gland cancer - cancerous tumors, including adrenocortical carcinoma and neuroblastoma
  • Congenital Adrenal Hyperplasia (CAH) - a group of inherited disorders in which the adrenal glands don't make enough cortisol. The most common type is 21-hydroxylase deficiency (also called CAH1). In the United States, newborn babies get a blood test to see if they have CAH. People born with CAH may not have symptoms until childhood or later in life.

What causes adrenal gland disorders?

The cause of adrenal gland disorders depends on the type of disorder you have. Causes can include:

  • Medicines such as steroids
  • A problem in another gland, such as the pituitary gland. The pituitary gland releases hormones that affect how the adrenal glands work.
  • Changes in genes (mutations). These changes can cause the adrenal glands to make too much or too little of one or more hormones.
  • Infections

In many cases the cause of the problem isn't clear.

How are adrenal gland disorders diagnosed?

Health care providers use different tests to check for adrenal disorders depending on your symptoms and health history. For example, you may have tests of your blood, urine (pee), or saliva (spit). These tests check your hormone levels. Your provider may order x-rays, CT scans, or MRI scans to look for tumors.

What are the treatments for adrenal gland disorders?

Different types of adrenal gland disorders have different treatments. They include medicines and surgery. Radiation therapy is sometimes a treatment for tumors. There are treatments to cure certain adrenal gland disorders. For other disorders, treatments can manage your symptoms.

NIH: National Institute of Child Health and Human Development


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.