2024 ICD-10-CM Diagnosis Code E16.4

Increased secretion of gastrin

ICD-10-CM Code:
E16.4
ICD-10 Code for:
Increased secretion of gastrin
Is Billable?
Yes - Valid for Submission
Chronic Condition Indicator: [1]
Chronic
Code Navigator:

Code Classification

  • Endocrine, nutritional and metabolic diseases
    (E00–E89)
    • Other disorders of glucose regulation and pancreatic internal secretion
      (E15-E16)
      • Other disorders of pancreatic internal secretion
        (E16)

E16.4 is a billable diagnosis code used to specify a medical diagnosis of increased secretion of gastrin. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2023 through September 30, 2024.

Approximate Synonyms

The following clinical terms are approximate synonyms or lay terms that might be used to identify the correct diagnosis code:

  • Abnormal hormone secretion
  • Abnormal hormone secretion
  • Abnormal hormone secretion
  • Abnormal hormone secretion
  • Abnormal hormone secretion
  • Abnormality of secretion of gastrin
  • Abnormality of secretion of gastrin
  • Abnormality of secretion of gastrin
  • Abnormality of secretion of gastrin
  • Abnormality of secretion of gastrin
  • Anastomotic ulcer due to Zollinger-Ellison syndrome
  • Drug-induced hypergastrinemia
  • Duodenal ulcer due to Zollinger-Ellison syndrome
  • Familial hypergastrinemic duodenal ulcer
  • Gastric ulcer due to Zollinger-Ellison syndrome
  • Gastrinoma
  • Hyperplasia of islet alpha cells with gastrin excess
  • Impaired acid inhibition of gastrin release
  • Increased gastrin secretion
  • Increased gastrin secretion
  • Increased gastrin secretion
  • Islet cell hyperplasia
  • Megaloblastic anemia due to Zollinger-Ellison syndrome
  • Zollinger-Ellison syndrome

Clinical Classification

Clinical Information

  • Gastrinoma

    a gastrin-secreting neuroendocrine tumor of the non-beta islet cells, the gastrin-secreting cells. this type of tumor is primarily located in the pancreas or the duodenum. majority of gastrinomas are malignant. they metastasize to the liver; lymph nodes; and bone but rarely elsewhere. the presence of gastrinoma is one of three requirements to be met for identification of zollinger-ellison syndrome, which sometimes occurs in families with multiple endocrine neoplasia type 1; (men 1).

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.


Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • Hypergastrinemia
  • Hyperplasia of pancreatic endocrine cells with gastrin excess
  • Zollinger-Ellison syndrome

Index to Diseases and Injuries References

The following annotation back-references for this diagnosis code are found in the injuries and diseases index. The Index to Diseases and Injuries is an alphabetical listing of medical terms, with each term mapped to one or more ICD-10-CM code(s).

Convert E16.4 to ICD-9-CM

  • ICD-9-CM Code: 251.5 - Abnorm secretion gastrin

Patient Education


Pancreatic Diseases

The pancreas is a gland behind your stomach and in front of your spine. It produces juices that help break down food and hormones that help control blood sugar levels. Problems with the pancreas can lead to many health problems. These include:

  • Pancreatitis, or inflammation of the pancreas: This happens when digestive enzymes start digesting the pancreas itself
  • Pancreatic cancer
  • Cystic fibrosis, a genetic disorder in which thick, sticky mucus can also block tubes in your pancreas

The pancreas also plays a role in diabetes. In type 1 diabetes, the beta cells of the pancreas no longer make insulin because the body's immune system has attacked them. In type 2 diabetes, the pancreas loses the ability to secrete enough insulin in response to meals.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.

Footnotes

[1] Chronic - a chronic condition code indicates a condition lasting 12 months or longer and its effect on the patient based on one or both of the following criteria:

  • The condition results in the need for ongoing intervention with medical products,treatment, services, and special equipment
  • The condition places limitations on self-care, independent living, and social interactions.