Version 2024

2024 ICD-10-CM Diagnosis Code E16

Other disorders of pancreatic internal secretion

ICD-10-CM Code:
E16
ICD-10 Code for:
Other disorders of pancreatic internal secretion
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Endocrine, nutritional and metabolic diseases
    (E00–E89)
    • Other disorders of glucose regulation and pancreatic internal secretion
      (E15-E16)
      • Other disorders of pancreatic internal secretion
        (E16)

E16 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of other disorders of pancreatic internal secretion. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Specific Coding Applicable to Other disorders of pancreatic internal secretion

Non-specific codes like E16 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for other disorders of pancreatic internal secretion:

  • Use E16.0 for Drug-induced hypoglycemia without coma - BILLABLE CODE

  • Use E16.1 for Other hypoglycemia - BILLABLE CODE

  • Use E16.2 for Hypoglycemia, unspecified - BILLABLE CODE

  • Use E16.3 for Increased secretion of glucagon - BILLABLE CODE

  • Use E16.4 for Increased secretion of gastrin - BILLABLE CODE

  • Use E16.8 for Other specified disorders of pancreatic internal secretion - BILLABLE CODE

  • Use E16.9 for Disorder of pancreatic internal secretion, unspecified - BILLABLE CODE

Patient Education


Pancreatic Diseases

The pancreas is a gland behind your stomach and in front of your spine. It produces juices that help break down food and hormones that help control blood sugar levels. Problems with the pancreas can lead to many health problems. These include:

  • Pancreatitis, or inflammation of the pancreas: This happens when digestive enzymes start digesting the pancreas itself
  • Pancreatic cancer
  • Cystic fibrosis, a genetic disorder in which thick, sticky mucus can also block tubes in your pancreas

The pancreas also plays a role in diabetes. In type 1 diabetes, the beta cells of the pancreas no longer make insulin because the body's immune system has attacked them. In type 2 diabetes, the pancreas loses the ability to secrete enough insulin in response to meals.


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.