2024 ICD-10-CM Diagnosis Code E05.9

Thyrotoxicosis, unspecified

ICD-10-CM Code:
E05.9
ICD-10 Code for:
Thyrotoxicosis, unspecified
Is Billable?
Not Valid for Submission
Code Navigator:

Code Classification

  • Endocrine, nutritional and metabolic diseases
    (E00–E89)
    • Disorders of thyroid gland
      (E00-E07)
      • Thyrotoxicosis [hyperthyroidism]
        (E05)

E05.9 is a non-specific and non-billable diagnosis code code, consider using a code with a higher level of specificity for a diagnosis of thyrotoxicosis, unspecified. The code is not specific and is NOT valid for the year 2024 for the submission of HIPAA-covered transactions. Category or Header define the heading of a category of codes that may be further subdivided by the use of 4th, 5th, 6th or 7th characters.

Unspecified diagnosis codes like E05.9 are acceptable when clinical information is unknown or not available about a particular condition. Although a more specific code is preferable, unspecified codes should be used when such codes most accurately reflect what is known about a patient's condition. Specific diagnosis codes should not be used if not supported by the patient's medical record.

Specific Coding Applicable to Thyrotoxicosis, unspecified

Non-specific codes like E05.9 require more digits to indicate the appropriate level of specificity. Consider using any of the following ICD-10-CM codes with a higher level of specificity when coding for thyrotoxicosis, unspecified:

  • Use E05.90 for Thyrotoxicosis, unspecified without thyrotoxic crisis or storm - BILLABLE CODE

  • Use E05.91 for Thyrotoxicosis, unspecified with thyrotoxic crisis or storm - BILLABLE CODE

Clinical Information

  • Thyrotoxicosis

    a hypermetabolic syndrome caused by excess thyroid hormones which may come from endogenous or exogenous sources. the endogenous source of hormone may be thyroid hyperplasia; thyroid neoplasms; or hormone-producing extrathyroidal tissue. thyrotoxicosis is characterized by nervousness; tachycardia; fatigue; weight loss; heat intolerance; and excessive sweating.
  • Chronic Thyroiditis with Transient Thyrotoxicosis|Chronic thyroiditis with transient thyrotoxicosis

    persistent and long-standing thyroiditis associated with temporary elevations of thyroid hormones.
  • Neonatal Thyrotoxicosis|Infantile Hyperthyroidism

    a hypermetabolic syndrome characterized by tachycardia, palpitations, tremor, weight loss, and moist skin that is caused by the elevation of thyroid hormone levels in the serum of the newborn infant or thyroid-axis receptor activation, most commonly due to transplacental passage of thyroid stimulating globulins.
  • Other Thyrotoxicosis with Thyrotoxic Crisis or Storm|Other thyrotoxicosis with thyrotoxic crisis or storm

    evidence of other thyrotoxicosis with thyrotoxic crisis or storm not specified elsewhere.
  • Other Thyrotoxicosis without Thyrotoxic Crisis or Storm|Other thyrotoxicosis without thyrotoxic crisis or storm

    evidence of other thyrotoxicosis without thyrotoxic crisis or storm not specified elsewhere.
  • Thyrotoxicosis

    a hypermetabolic syndrome caused by the elevation of thyroid hormone levels in the serum. signs and symptoms include tachycardia, palpitations, tremor, weight loss, warm weather intolerance, and moist skin. causes include graves disease, toxic nodular goiter, toxic thyroid nodule, and lymphocytic thyroiditis.
  • Thyrotoxicosis Factitia with Thyrotoxic Crisis or Storm|Thyrotoxicosis factitia with thyrotoxic crisis or storm

    evidence of thyrotoxicosis factitia with thyrotoxic crisis or storm.
  • Thyrotoxicosis Factitia without Thyrotoxic Crisis or Storm|Thyrotoxicosis factitia without thyrotoxic crisis or storm

    evidence of thyrotoxicosis factitia without thyrotoxic crisis or storm.
  • Thyrotoxicosis from Ectopic Thyroid Tissue with Thyrotoxic Crisis|Thyrotoxicosis from ectopic thyroid tissue with thyrotoxic crisis

    evidence of thyrotoxicosis from ectopic thyroid tissue with thyrotoxic crisis.
  • Thyrotoxicosis from Ectopic Thyroid Tissue without Thyrotoxic Crisis|Thyrotoxicosis from ectopic thyroid tissue without thyrotoxic crisis

    evidence of thyrotoxicosis from ectopic thyroid tissue without thyrotoxic crisis.
  • Thyrotoxicosis with Diffuse Goiter with Thyrotoxic Crisis or Storm|Thyrotoxicosis with diffuse goiter with thyrotoxic crisis or storm

    evidence of thyrotoxicosis with diffuse goiter with thyrotoxic crisis or storm.
  • Thyrotoxicosis with Diffuse Goiter without Thyrotoxic Crisis|Thyrotoxicosis with diffuse goiter without thyrotoxic crisis

    evidence of thyrotoxicosis with diffuse goiter without thyrotoxic crisis.
  • Thyrotoxicosis with Toxic Multinodular Goiter with Thyrotoxic Crisis|Thyrotoxicosis with toxic multinodular goiter with thyrotoxic crisis

    evidence of thyrotoxicosis with toxic multinodular goiter with thyrotoxic crisis.
  • Thyrotoxicosis with Toxic Multinodular Goiter without Thyrotoxic Crisis|Thyrotoxicosis with toxic multinodular goiter without thyrotoxic crisis

    evidence of thyrotoxicosis with toxic multinodular goiter without thyrotoxic crisis.
  • Thyrotoxicosis with Toxic Single Thyroid Nodule with Thyrotoxic Crisis|Thyrotoxicosis with toxic single thyroid nodule with thyrotoxic crisis

    evidence of thyrotoxicosis with toxic single thyroid nodule with thyrotoxic crisis.
  • Thyrotoxicosis with Toxic Single Thyroid Nodule without Thyrotoxic Crisis|Thyrotoxicosis with toxic sing thyroid nodule without thyrotoxic crisis

    evidence of thyrotoxicosis with toxic single thyroid nodule without thyrotoxic crisis.
  • Thyrotoxicosis, Unspecified with Thyrotoxic Crisis or Storm|Thyrotoxicosis, unspecified with thyrotoxic crisis or storm

    evidence of thyrotoxicosis, unspecified with thyrotoxic crisis or storm.
  • Thyrotoxicosis, Unspecified without Thyrotoxic Crisis or Storm|Thyrotoxicosis, unspecified without thyrotoxic crisis or storm

    evidence of thyrotoxicosis, unspecified without thyrotoxic crisis or storm.

Tabular List of Diseases and Injuries

The following annotation back-references are applicable to this diagnosis code. The Tabular List of Diseases and Injuries is a list of ICD-10-CM codes, organized "head to toe" into chapters and sections with coding notes and guidance for inclusions, exclusions, descriptions and more.


Inclusion Terms

Inclusion Terms
These terms are the conditions for which that code is to be used. The terms may be synonyms of the code title, or, in the case of "other specified" codes, the terms are a list of the various conditions assigned to that code. The inclusion terms are not necessarily exhaustive. Additional terms found only in the Alphabetic Index may also be assigned to a code.
  • Hyperthyroidism NOS

Patient Education


Hyperthyroidism

What is hyperthyroidism?

Hyperthyroidism, or overactive thyroid, happens when your thyroid gland makes more thyroid hormones than your body needs.

Your thyroid is a small, butterfly-shaped gland in the front of your neck. It makes hormones that control the way the body uses energy. These hormones affect nearly every organ in your body and control many of your body's most important functions. For example, they affect your breathing, heart rate, weight, digestion, and moods. If not treated, hyperthyroidism can cause serious problems with your heart, bones, muscles, menstrual cycle, and fertility. But there are treatments that can help.

What causes hyperthyroidism?

Hyperthyroidism has several causes. They include:

  • Graves' disease, an autoimmune disorder in which your immune system attacks your thyroid and causes it to make too much hormone. This is the most common cause.
  • Thyroid nodules, which are growths on your thyroid. They are usually benign (not cancer). But they may become overactive and make too much thyroid hormone. Thyroid nodules are more common in older adults.
  • Thyroiditis, inflammation of the thyroid. It causes stored thyroid hormone to leak out of your thyroid gland.
  • Too much iodine. Iodine is found in some medicines, cough syrups, seaweed and seaweed-based supplements. Taking too much of them can cause your thyroid to make too much thyroid hormone.
  • Too much thyroid medicine. This can happen if people who take thyroid hormone medicine for hypothyroidism (underactive thyroid) take too much of it.

Who is at risk for hyperthyroidism?

You are at higher risk for hyperthyroidism if you:

  • Are a woman
  • Are older than age 60
  • Have been pregnant or had a baby within the past 6 months
  • Have had thyroid surgery or a thyroid problem, such as goiter
  • Have a family history of thyroid disease
  • Have pernicious anemia, in which the body cannot make enough healthy red blood cells because it does not have enough vitamin B12
  • Have type 1 diabetes or primary adrenal insufficiency, a hormonal disorder
  • Get too much iodine, from eating large amounts of foods containing iodine or using iodine-containing medicines or supplements

What are the symptoms of hyperthyroidism?

The symptoms of hyperthyroidism can vary from person to person and may include:

  • Nervousness or irritability
  • Fatigue
  • Muscle weakness
  • Trouble tolerating heat
  • Trouble sleeping
  • Tremor, usually in your hands
  • Rapid and irregular heartbeat
  • Frequent bowel movements or diarrhea
  • Weight loss
  • Mood swings
  • Goiter, an enlarged thyroid that may cause your neck to look swollen. Sometimes it can cause trouble with breathing or swallowing.

Adults over age 60 may have different symptoms than younger adults. For example, they may lose their appetite or withdraw from other people. Sometimes this can be mistaken for depression or dementia.

What other problems can hyperthyroidism cause?

If hyperthyroidism isn't treated, it can cause some serious health problems, including:

  • An irregular heartbeat that can lead to blood clots, stroke, heart failure, and other heart problems
  • An eye disease called Graves' ophthalmopathy. It can cause double vision, light sensitivity, and eye pain. In rare cases, it can lead to vision loss.
  • Thinning bones and osteoporosis
  • Fertility problems in women
  • Complications in pregnancy, such as premature birth, low birth weight, high blood pressure in pregnancy, and miscarriage

How is hyperthyroidism diagnosed?

Your health care provider may use many tools to make a diagnosis:

  • A medical history, including asking about symptoms
  • A physical exam
  • Thyroid tests, such as
    • TSH, T3, T4, and thyroid antibody blood tests
    • Imaging tests, such as a thyroid scan, ultrasound, or radioactive iodine uptake test. A radioactive iodine uptake test measures how much radioactive iodine your thyroid takes up from your blood after you swallow a small amount of it.

What are the treatments for hyperthyroidism?

The treatments for hyperthyroidism include medicines, radioiodine therapy, and thyroid surgery:

  • Medicines for hyperthyroidism include
    • Antithyroid medicines, which cause your thyroid to make less thyroid hormone. You probably need to take the medicines for 1 to 2 years. In some cases, you might need to take the medicines for several years. This is the simplest treatment, but it is often not a permanent cure.
    • Beta blocker medicines, which can reduce symptoms such as tremors, rapid heartbeat, and nervousness. They work quickly and can help you feel better until other treatments take effect.
  • Radioiodine therapy is a common and effective treatment for hyperthyroidism. It involves taking radioactive iodine by mouth as a capsule or liquid. This slowly destroys the cells of the thyroid gland that produce thyroid hormone. It does not affect other body tissues. Almost everyone who has radioactive iodine treatment later develops hypothyroidism. This is because the thyroid hormone-producing cells have been destroyed. But hypothyroidism is easier to treat and causes fewer long-term health problems than hyperthyroidism.
  • Surgery to remove part or most of the thyroid gland is done in rare cases. It might be an option for people with large goiters or pregnant women who cannot take antithyroid medicines. If you have all of your thyroid removed, you will need to take thyroid medicines for the rest of your life. Some people who have part of their thyroid removed also need to take medicines.

If you have hyperthyroidism, it's important not to get too much iodine. Talk to your health care provider about which foods, supplements, and medicines you need to avoid.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases


[Learn More in MedlinePlus]

Code History

  • FY 2024 - No Change, effective from 10/1/2023 through 9/30/2024
  • FY 2023 - No Change, effective from 10/1/2022 through 9/30/2023
  • FY 2022 - No Change, effective from 10/1/2021 through 9/30/2022
  • FY 2021 - No Change, effective from 10/1/2020 through 9/30/2021
  • FY 2020 - No Change, effective from 10/1/2019 through 9/30/2020
  • FY 2019 - No Change, effective from 10/1/2018 through 9/30/2019
  • FY 2018 - No Change, effective from 10/1/2017 through 9/30/2018
  • FY 2017 - No Change, effective from 10/1/2016 through 9/30/2017
  • FY 2016 - New Code, effective from 10/1/2015 through 9/30/2016. This was the first year ICD-10-CM was implemented into the HIPAA code set.